Ellison Institute, LLC

A leading technology institute in Oxford seeks a skilled Translational Scientist to translate foundational work into real-world applications. Responsibilities include designing lab experiments, developing experimental workflows, and mentoring lab technicians. Ideal candidates should have an MSc or PhD in a relevant field with strong wet-lab experience, particularly in molecular cloning and bacterial genome editing. Competitive salary and advanced facilities are provided, with a commitment to professional growth in an inclusive environment.

At the Ellison Institute of Technology (EIT), we're on a mission to translate scientific discovery into real world impact. We bring together visionary scientists, technologists, engineers, researchers, educators, and innovators to tackle humanity's greatest challenges in four transformative areas: Health, Medical Science & Generative Biology Food Security & Sustainable Agriculture Climate Change & Managing CO Artificial Intelligence & Robotics Led by Founding Director Jason Chin, the Generative Biology Institute (GBI) at EIT is tackling key challenges in making biology engineerable and unlocking its power for humanity. The vision of GBI is to lay the foundations for engineering biology and to unlock its potential for good, addressing challenges in health, agriculture, clean energy, and more. Your Role: We are seeking an experienced and detail oriented Research Assistant to join our Flow Cytometry team within a dynamic research environment. The successful candidate will support departmental research by providing expertise in flow cytometry analysis and cell sorting, working closely with diverse research groups in GBI to enable cutting edge discoveries. Key Responsibilities: Operate flow cytometry analysers and cell sorters, ensuring accurate and high quality analytical and sorting performance. Develop and implement advanced flow cytometry workflows, adopting emerging technology and approaches for the characterisation of diverse sample types, including engineered cells and microbial populations. Perform data analysis using flow cytometry software (e.g. FlowJo), providing accurate and meaningful interpretation to support research outcomes. Provide hands on training and ongoing support to research colleagues, promoting user autonomy and best operational practice. Ensure strict adherence to workflow protocols and safety guidelines when handling and sorting biological samples. Collaborate with the team to maintain and update standard operating procedures (SOPs) and COSHH documentation, ensuring compliance and consistency. Maximise performance and instrument uptime through the maintenance, calibration, and troubleshooting of cell analysers and sorters, including coordination of engineer visits for repairs. Execute daily quality control procedures. Maintain consumable stock levels, ensuring efficient and cost effective procurement when required. Work with Tech Hub colleagues to support operation of the Nikon confocal microscope, including coordination of user booking, assistance with training, and routine maintenance. Essential Knowledge, Skills and Experience: A degree in Life Sciences, Bioengineering, or a related field, with significant hands on laboratory experience. Practical experience in fluorescence based sample staining (e.g. antibody labelling) for flow cytometry or microscopy, including working with mammalian or microbial cells, and murine or human tissues. Ability to understand the technical complexity in flow cytometry instrumentation and applications, aligning facility capabilities with the broader objectives of the research programme. Good knowledge of flow cytometry principles; experience in troubleshooting and optimising sample preparation and staining procedures. Experience in supporting laboratory activities and operation, including ordering consumables, maintaining accurate records, and contributing to SOPs, risk assessment and COSHH documentation. Experience in training or mentoring others, with a proactive and collaborative approach. Strong organisational skills and attention to detail, with the ability to work methodically under time pressure while maintaining high standards. Exceptional communication skills, with the ability to engage diverse internal and external audiences. Desirable skills: Flow cytometry applications such as DNA analysis, small particle detection. Flow cytometry data analysis using third party software such as FlowJo, FCS Express or Python/R. Cell sorting of microbial and/or mammalian cells. Experience with confocal microscopy or other fluorescence imaging techniques. Our Benefits: Salary: Competitive + travel allowance + bonus Enhanced holiday pay Pension Life Assurance Income Protection Private Medical Insurance Hospital Cash Plan Therapy Services Perk Box Electric Car Scheme Working Together - What It Involves: You must have the right to work permanently in the UK with a willingness to travel as necessary. In certain cases, we can consider sponsorship, and this will be assessed on a case by case basis. You will live in, or within easy commuting distance of, Oxford (or be willing to relocate).

A prestigious research institute in Oxford seeks a Scientist or Senior Scientist to advance sequencing-based diagnostics in infectious diseases. This role involves designing and optimising sequencing assays and collaborating with a multidisciplinary team. The ideal candidate has a PhD in a relevant field and experience with molecular biology techniques. Benefits include competitive salary, enhanced holiday pay, and private medical insurance, among others. Candidates should be willing to work fully on-site in Oxford.

At the Ellison Institute of Technology (EIT), we're on a mission to translate scientific discovery into real world impact. We bring together visionary scientists, technologists, engineers, researchers, educators and innovators to tackle humanity's greatest challenges in four transformative areas: Health, Medical Science & Generative Biology Food Security & Sustainable Agriculture Climate Change & Managing CO Artificial Intelligence & Robotics This is ambitious work - work that demands curiosity, courage, and a relentless drive to make a difference. At EIT, you'll join a community built on excellence, innovation, tenacity, trust, and collaboration, where bold ideas become real-world breakthroughs. Together, we push boundaries, embrace complexity, and create solutions to scale ideas from lab to society. Explore more at . Welcome to the Pathogen Project Within this ecosystem, the Pathogen Mission exemplifies EIT's commitment to transformative science. It aims to revolutionise the diagnosis and treatment of infectious diseases by leveraging whole genome sequencing (WGS)-based metagenomic and pathogen specific analytical tools. This remit includes the development of a decentralised, sample to answer sequencing diagnostic platform for infectious diseases, enabling rapid and accurate analysis of patient samples without prior assumptions. Supported by Oracle Inc.'s cloud computing scale and security infrastructure, the Pathogen Mission is progressing towards certified diagnostic products for deployment in laboratories, hospitals, and public health organisations worldwide. Your Role We are seeking a Scientist or Senior Scientist with a strong interest in method development to join our growing Applications team, focused on advancing sequencing based diagnostics. In this role, you will contribute to the design and optimisation of novel targeted and semi targeted approaches for the rapid sequencing of clinically relevant pathogens. This laboratory based position encompasses end to end experimental workflows, including sample preparation, target enrichment and amplification, library preparation, and sequencing. You will support the development of strategies for comprehensive, high sensitivity sequencing across a large number of targets, using approaches such as targeted amplification, hybridisation, and related techniques. The role encourages creative problem solving, with opportunities to propose, explore, and evaluate new ideas. You will work collaboratively within a multidisciplinary team of microbiologists, molecular biologists, engineers, and data scientists to develop assays for integration into an automated, device based platform. Drawing on your experience, you will help define experimental strategies, design and execute studies, and contribute to advancing the application of sequencing technologies in pathogen detection and related areas. Key Responsibilities Design, develop, and optimise end to end sequencing assays (targeted and semi targeted) Execute experiments, analyse and interpret data, and contribute ideas for improvement Troubleshoot complex technical challenges across a range of sample types Maintain clear documentation to support reproducibility of experimental work Collaborate closely with colleagues across disciplines to progress shared goals Contribute to scientific discussions and decision making as projects evolve Essential Knowledge, Skills, and Experience PhD in molecular biology, microbiology, genomics, biochemistry or a related field Experience using molecular biology techniques (e.g. PCR, RT PCR, nucleic acid extraction, library preparation) Experience developing and optimising PCRs and/or related experimental workflows Ability to troubleshoot experimental challenges and adapt methods as needed Experience with DNA/RNA sequencing data Strong experimental design and data interpretation skills Good organisation, record keeping and communication skills Desirable We recognise that strong candidates may not meet every criterion below. Experience in any of the following would be beneficial: Multiplex PCR assay development, particularly for sequencing applications Enrichment or capture methods for pathogens or pathogen derived nucleic acids Work with bacteria, fungi, viruses, or other pathogens Handling clinical samples RNA based workflows (e.g. transcriptomics, viral genomics) Background in virology Exposure to metagenomics workflows Biochemistry knowledge relevant to assay development (e.g. enzyme optimisation, reaction conditions, assay development) Key Attributes Scientific and Technical Enjoys exploring new ideas and approaches to experimental challenges Curious and motivated to solve complex problems Able to balance scientific rigour with speed and pragmatism Working Style and Collaboration Takes ownership of work while valuing collaboration and shared success Proactive and supportive team member, with a willingness to contribute beyond immediate responsibilities Comfortable working in a dynamic research environment, with support from colleagues Our Benefits Salary: Competitive + travel allowance + bonus Enhanced holiday pay Pension Life Assurance Income Protection Private Medical Insurance Hospital Cash Plan Therapy Services Perk Box Electric Car Scheme Working Together - What It Involves You must have the right to work permanently in the UK with a willingness to travel as necessary. In certain cases, we can consider sponsorship, and this will be assessed on a case by case basis. For this role we would expect someone to be fully on site in Oxford You will live in, or within easy commuting distance of, Oxford (or be willing to relocate).

A leading research organization in Oxford is seeking a Senior or Non Senior Scientist with expertise in computational methods for genomic sequencing. The successful candidate will develop novel analytical approaches and collaborate with interdisciplinary teams to enhance infectious disease diagnostics. Essential qualifications include a PhD in a related field and experience in bioinformatics tools and methodologies. The role offers competitive salary and benefits in a dynamic, innovative environment.

Overview At the Ellison Institute of Technology (EIT), we're on a mission to translate scientific discovery into real world impact. We bring together visionary scientists, technologists, engineers, researchers, educators and innovators to tackle humanity's greatest challenges in four transformative areas: Health, Medical Science & Generative Biology Food Security & Sustainable Agriculture Climate Change & Managing CO Artificial Intelligence & Robotics This is ambitious work - work that demands curiosity, courage, and a relentless drive to make a difference. At EIT, you'll join a community built on excellence, innovation, tenacity, trust, and collaboration, where bold ideas become real-world breakthroughs. Explore more at . Welcome to the Pathogen Project: Within this ecosystem, the Pathogen Project exemplifies EIT's dedication to ground-breaking science. It seeks to transform pathogen risk management, detection and response by leveraging Whole Genome Sequencing (WGS)-based metagenomic and pathogen-specific analytical tools. The goal is to power metagenomic devices using long-read sequencing technologies by building a comprehensive database of pathogen information to inform response. Enabled by Oracle Inc.'s cloud-computing scale and security, the Pathogen Project is advancing toward certified diagnostic tools for deployment in laboratories, hospitals, and public health organisations worldwide. Your Role: At EIT we are seeking an experienced and detailed orientated (Senior or Non Senior) Scientist with recognised expertise in developing computational methods and algorithms for genomic sequencing data analysis. This is an exciting opportunity to develop novel computational approaches for microbial data that will become part of our diagnostic products and thus help shape the future of infectious disease diagnostics. Reporting to the Lead Scientist in Computational Genomics, you will work closely with computational scientists, bioinformaticians, software engineers, and our database and data platform teams to deliver scientifically rigorous, scalable, and clinically relevant innovation in the microbial genomics space. Key Responsibilities: Design, develop and evaluate novel computational approaches in areas such as genome assembly, binning, and functional characterisation of genomes from metagenomic sequencing data Collaborate with scientists across EIT to apply the latest developments in AI/ML to real-world challenges in the pathogen space Work with bioinformaticians and software engineers to implement methods in scalable, reproducible, and modular workflows Perform rigorous benchmarking using public and internal datasets, and guide experimental validation efforts in collaboration with our wet-lab teams Communicate technical concepts to broad audiences and collaborate with interdisciplinary colleagues across the organisation Essential Knowledge, Skills and Experience: PhD or equivalent experience in bioinformatics, computational biology, computer science, or a related quantitative field Senior: At least 3 years of postdoctoral or industry experience developing computational methods for next-generation sequencing data Non-Senior: Hands-on experience developing computational methods for next-generation sequencing data Significant experience with bioinformatics methods such as efficient search and storage of DNA sequences, genome assembly, genome annotation, pangenomes, phylogenetics, and comparative genomics Solid understanding of data structures, algorithms, and statistical methods (e.g. De Bruijn graphs, hashing, Burrows-Wheeler transform, Bayesian methods, mixed models, dimensionality reduction, embeddings) Experience with machine learning in the context of biological data, particularly sequencing data Proficient in the use of command-line interfaces, low and high-level programming languages (e.g. Python, C, C++, Rust) and modern software development techniques (version control, CI/CD) Track record of scientific output and engagement with the computational genomics community Desirable Knowledge, Skills and Experience: Experience working with microbial genomes and shotgun metagenomics data Experience working with long-read sequencing data (ONT) Experience with bioinformatics workflow management (e.g. Nextflow) and cloud computing (e.g. OCI, AWS, GCP) Contributions to open-source bioinformatics software Previous experience mentoring or line-managing scientists (For Senior) Key Attributes: Strategic thinker with the ability to translate scientific insights into practical solutions Effective communicator and enthusiastic knowledge sharer across disciplines Rigorous and detail-oriented with a commitment to reproducibility and benchmarking Comfortable in a fast-paced, interdisciplinary environment and able to adapt to evolving priorities Collaborative ethos with the ability to work across teams and domains Our Benefits: Salary: Competitive + travel allowance + bonus Enhanced holiday + options to buy additional days Pension Life Assurance Income Protection Private Medical Insurance Hospital Cash Plan Therapy Services Perk Box Electric Car Scheme Childcare benefit Working Together - What It Involves: You must have the permanent right to work in the UK and be willing to travel when required. Given the specialised nature of this role, we can consider sponsorship for candidates who meet the expectations outlined in the job description. You will live in, or within easy commuting distance of, Oxford (or be willing to relocate).

A research and development organization is seeking an experienced Team Coordinator to join their MDLS team in Oxford. The successful candidate will manage team calendars, provide administrative support, and ensure smooth day to day operations. Essential skills include experience in a coordinator role, proficiency in Microsoft 365, and strong communication abilities. This position requires on-site presence five days a week, with some flexibility.