BioLegend, Inc.
Macclesfield, Cheshire
Job Description Summary The (Senior) Laboratory Manager reports to the Director, Laboratory Operations and oversees testing of clinical samples at Alderley Park. In addition, this role provides strategic leadership and direct management of laboratory teams, ensuring staff are supported, coached, and developed to achieve both individual and organizational goals. The (Senior) Laboratory Manager is accountable for day-to-day laboratory operations, resource allocation, safety compliance, and fostering a culture of collaboration, innovation, and continuous improvement. About the Role Provide on-site leadership for a high-throughput clinical genome sequencing laboratory, including technical troubleshooting, developing and writing operational procedures, setting laboratory key performance indicators, and establishing quality metrics. Deliver regulatory, due diligence, and internal auditing support. Must have experience working in an ISO 15189 or CAP diagnostic laboratory and be able to apply the associated requirements to clinical diagnostic operations. This role requires a proactive leader who can balance scientific rigor with operational excellence, guiding teams through complex projects while ensuring compliance, efficiency, and staff development. Duties and Responsibilities Team Leadership & Management Supervise, mentor, and develop laboratory staff, including scientists, technicians, and support personnel. Conduct performance reviews, set clear objectives, and foster accountability. Promote a positive and inclusive team culture that encourages collaboration, innovation, and professional growth. Laboratory Operations Design and implement processes and procedures to ensure efficient turnaround times and accuracy of results. Oversee daily laboratory operations, including workflow optimization, resource allocation, and equipment maintenance. Ensure strict adherence to established quality control guidelines and safety protocols. Strategic & Financial Management Prepare and manage laboratory budgets, monitor expenditures, and optimize resource utilization. Establish and track laboratory KPIs and quality metrics to drive continuous improvement. Compliance & Accreditation Ensure all processes comply with national regulations, organizational policies, and accreditation requirements. Maintain ISO 15189, CAP, and other accreditation standards, including preparation for audits and inspections. Continuous Improvement & Innovation Lead initiatives for process improvement, automation, and adoption of new technologies. Encourage staff participation in problem-solving and innovation to enhance laboratory efficiency and service delivery. Stakeholder Engagement Collaborate with customers and cross-functional teams to align laboratory operations with clinical and research objectives. Communicate effectively with internal and external stakeholders, providing updates on laboratory performance and compliance. Experience Minimum of a Master's degree in a relevant subject; PhD desirable. Extensive clinical experience with various techniques; high-throughput DNA sequencing in a commercial, academic, or government laboratory desirable. Experience with clinical assay development, process development, and project management. Proven track record in team leadership, staff development, and laboratory management. Strong background in Quality Assurance and Quality Control applications in clinical diagnostics. Detail-oriented, highly organized, with excellent verbal and written communication skills. Ability to troubleshoot technical applications and manage laboratory automation systems. Knowledge, Skills, and Abilities Leadership Skills: Ability to inspire, motivate, and develop staff while managing performance and fostering collaboration. Language: Ability to read and interpret documents such as safety rules, operating and maintenance instructions, and procedure manuals. Ability to write routine reports and correspondence. Math Ability: Ability to work with mathematical concepts such as probability and statistical inference. Ability to apply concepts such as fractions, percentages, ratios, and proportions to practical situations. Reasoning Ability: Ability to define problems, collect data, establish facts, and draw valid conclusions. Ability to solve practical problems and deal with a variety of concrete variables in situations where only limited standardization exists. Computer Skills: Proficiency in Microsoft Word, Outlook, and Excel, with the ability to operate laboratory computer systems. Special Skills: Effective interpersonal communication across departments and teams. Strong knowledge of quality control practices and regulations of UKAS, ISO 15189, CAP, and other regulatory agencies.
Job Description Summary The (Senior) Laboratory Manager reports to the Director, Laboratory Operations and oversees testing of clinical samples at Alderley Park. In addition, this role provides strategic leadership and direct management of laboratory teams, ensuring staff are supported, coached, and developed to achieve both individual and organizational goals. The (Senior) Laboratory Manager is accountable for day-to-day laboratory operations, resource allocation, safety compliance, and fostering a culture of collaboration, innovation, and continuous improvement. About the Role Provide on-site leadership for a high-throughput clinical genome sequencing laboratory, including technical troubleshooting, developing and writing operational procedures, setting laboratory key performance indicators, and establishing quality metrics. Deliver regulatory, due diligence, and internal auditing support. Must have experience working in an ISO 15189 or CAP diagnostic laboratory and be able to apply the associated requirements to clinical diagnostic operations. This role requires a proactive leader who can balance scientific rigor with operational excellence, guiding teams through complex projects while ensuring compliance, efficiency, and staff development. Duties and Responsibilities Team Leadership & Management Supervise, mentor, and develop laboratory staff, including scientists, technicians, and support personnel. Conduct performance reviews, set clear objectives, and foster accountability. Promote a positive and inclusive team culture that encourages collaboration, innovation, and professional growth. Laboratory Operations Design and implement processes and procedures to ensure efficient turnaround times and accuracy of results. Oversee daily laboratory operations, including workflow optimization, resource allocation, and equipment maintenance. Ensure strict adherence to established quality control guidelines and safety protocols. Strategic & Financial Management Prepare and manage laboratory budgets, monitor expenditures, and optimize resource utilization. Establish and track laboratory KPIs and quality metrics to drive continuous improvement. Compliance & Accreditation Ensure all processes comply with national regulations, organizational policies, and accreditation requirements. Maintain ISO 15189, CAP, and other accreditation standards, including preparation for audits and inspections. Continuous Improvement & Innovation Lead initiatives for process improvement, automation, and adoption of new technologies. Encourage staff participation in problem-solving and innovation to enhance laboratory efficiency and service delivery. Stakeholder Engagement Collaborate with customers and cross-functional teams to align laboratory operations with clinical and research objectives. Communicate effectively with internal and external stakeholders, providing updates on laboratory performance and compliance. Experience Minimum of a Master's degree in a relevant subject; PhD desirable. Extensive clinical experience with various techniques; high-throughput DNA sequencing in a commercial, academic, or government laboratory desirable. Experience with clinical assay development, process development, and project management. Proven track record in team leadership, staff development, and laboratory management. Strong background in Quality Assurance and Quality Control applications in clinical diagnostics. Detail-oriented, highly organized, with excellent verbal and written communication skills. Ability to troubleshoot technical applications and manage laboratory automation systems. Knowledge, Skills, and Abilities Leadership Skills: Ability to inspire, motivate, and develop staff while managing performance and fostering collaboration. Language: Ability to read and interpret documents such as safety rules, operating and maintenance instructions, and procedure manuals. Ability to write routine reports and correspondence. Math Ability: Ability to work with mathematical concepts such as probability and statistical inference. Ability to apply concepts such as fractions, percentages, ratios, and proportions to practical situations. Reasoning Ability: Ability to define problems, collect data, establish facts, and draw valid conclusions. Ability to solve practical problems and deal with a variety of concrete variables in situations where only limited standardization exists. Computer Skills: Proficiency in Microsoft Word, Outlook, and Excel, with the ability to operate laboratory computer systems. Special Skills: Effective interpersonal communication across departments and teams. Strong knowledge of quality control practices and regulations of UKAS, ISO 15189, CAP, and other regulatory agencies.
BioLegend, Inc.
Macclesfield, Cheshire
Purpose: The role of Laboratory Supervisor involves managing daily laboratory operations, ensuring the delivery of high-quality genomic analysis, and maintaining compliance with all regulatory standards. The successful candidate will play a key role in fostering a culture of excellence, innovation, and continuous improvement within our laboratory environment. Duties & Responsibilities: Lead and line manage laboratory technicians, providing guidance and technical support in the execution of pre-analytical, analytical and post analytical test processes. Coordinate with management to plan for staff scheduling and specimen receipt in meeting defined operational requirements for the day Support laboratory technicians during testing and act as a point of escalation for specimen and instrument issues, knowing how to troubleshoot routine problems and when to elevate breakdowns. Be responsible for the identification and escalation of non-conformities and the reporting of adverse events as critical components of the lab's Quality Performance Indicators, ensuring continuous monitoring and improvement of quality standards. Be accountable for achieving Turnaround Time (TAT) targets and minimising invalid result reporting as essential Key Performance Indicators (KPIs). Oversee continuous process and service improvements and work with R&D in proposing and implementing new strategies and technologies to enhance operational efficiency. Play a leading role in the laboratory's quality assurance programs, including audit preparation, policy development, and corrective action plans for non-conformances. Ensure instruments are in service, reagents are qualified, and PPE is stocked and staff training is up to date. Ensure continuous oversight of laboratory inventory levels and communicate to management in a timely manner. Assist in maintaining ISO 15189 and other accreditation standards. Minimum Experience: M.Sc or M.Res. degree or equivalent with specialized training and experience in molecular genetics, molecular biology, molecular pathology, or related field. A minimum of 5 years of clinical experience in genomics or molecular biology, including significant experience with high throughput DNA sequencing and nucleic acid-based assays, within a commercial, academic, or government laboratory. Previous supervisory or management experience in a laboratory setting is essential. Comprehensive knowledge of laboratory accreditation standards, particularly ISO 15189, and experience maintaining compliance with these and other regulatory requirements Proven leadership skills, with the ability to mentor, motivate, and guide a team towards achieving excellence in laboratory operations. Must be detail-oriented and highly organised with a strong practical understanding of clinical laboratory practices, protocols, and safety standards. Demonstrated ability to problem-solve and implement effective solutions in a fast-paced and evolving environment. Registration with the Health and Care Professions Council (HCPC) is highly desirable Knowledge, Skills, Abilities: Language:Ability to read and interpret documents such as safety rules, operating and maintenance instructions, and procedure manuals. Ability to write routine reports and correspondence. Maths Ability:Ability to work with mathematical concepts such as probability and statistical inference. Ability to apply concepts such as fractions, percentages, ratios, and proportions to practical situations. Reasoning Ability: Ability to define problems, collect data, establish facts, and draw valid conclusions. Ability to solve practical problems and deal with a variety of concrete variables in situations where only limited standardization exists. Ability to interpret a variety of instructions furnished in written, oral, diagram, or schedule form Computer Skills: To perform this job successfully, an individual should have knowledge of Microsoft Word, Outlook, and Microsoft Excel. Ability to operate laboratory computer systems. Special Skills:Demonstrate effective interpersonal communications between departments and co-workers. Communicate effectively (orally and written) with coworkers, employees of other departments, supervisors, and administration. Knowledge of quality control practices and requirements of UKAS, ISO 15189 CAP and other regulatory agencies. Working Conditions: Clinical Laboratory environment; exposure to blood borne pathogens, hazardous chemicals; must wear personal protective equipment including lab coat, gloves and completely closed footwear. Weekend rotation may be required.
Purpose: The role of Laboratory Supervisor involves managing daily laboratory operations, ensuring the delivery of high-quality genomic analysis, and maintaining compliance with all regulatory standards. The successful candidate will play a key role in fostering a culture of excellence, innovation, and continuous improvement within our laboratory environment. Duties & Responsibilities: Lead and line manage laboratory technicians, providing guidance and technical support in the execution of pre-analytical, analytical and post analytical test processes. Coordinate with management to plan for staff scheduling and specimen receipt in meeting defined operational requirements for the day Support laboratory technicians during testing and act as a point of escalation for specimen and instrument issues, knowing how to troubleshoot routine problems and when to elevate breakdowns. Be responsible for the identification and escalation of non-conformities and the reporting of adverse events as critical components of the lab's Quality Performance Indicators, ensuring continuous monitoring and improvement of quality standards. Be accountable for achieving Turnaround Time (TAT) targets and minimising invalid result reporting as essential Key Performance Indicators (KPIs). Oversee continuous process and service improvements and work with R&D in proposing and implementing new strategies and technologies to enhance operational efficiency. Play a leading role in the laboratory's quality assurance programs, including audit preparation, policy development, and corrective action plans for non-conformances. Ensure instruments are in service, reagents are qualified, and PPE is stocked and staff training is up to date. Ensure continuous oversight of laboratory inventory levels and communicate to management in a timely manner. Assist in maintaining ISO 15189 and other accreditation standards. Minimum Experience: M.Sc or M.Res. degree or equivalent with specialized training and experience in molecular genetics, molecular biology, molecular pathology, or related field. A minimum of 5 years of clinical experience in genomics or molecular biology, including significant experience with high throughput DNA sequencing and nucleic acid-based assays, within a commercial, academic, or government laboratory. Previous supervisory or management experience in a laboratory setting is essential. Comprehensive knowledge of laboratory accreditation standards, particularly ISO 15189, and experience maintaining compliance with these and other regulatory requirements Proven leadership skills, with the ability to mentor, motivate, and guide a team towards achieving excellence in laboratory operations. Must be detail-oriented and highly organised with a strong practical understanding of clinical laboratory practices, protocols, and safety standards. Demonstrated ability to problem-solve and implement effective solutions in a fast-paced and evolving environment. Registration with the Health and Care Professions Council (HCPC) is highly desirable Knowledge, Skills, Abilities: Language:Ability to read and interpret documents such as safety rules, operating and maintenance instructions, and procedure manuals. Ability to write routine reports and correspondence. Maths Ability:Ability to work with mathematical concepts such as probability and statistical inference. Ability to apply concepts such as fractions, percentages, ratios, and proportions to practical situations. Reasoning Ability: Ability to define problems, collect data, establish facts, and draw valid conclusions. Ability to solve practical problems and deal with a variety of concrete variables in situations where only limited standardization exists. Ability to interpret a variety of instructions furnished in written, oral, diagram, or schedule form Computer Skills: To perform this job successfully, an individual should have knowledge of Microsoft Word, Outlook, and Microsoft Excel. Ability to operate laboratory computer systems. Special Skills:Demonstrate effective interpersonal communications between departments and co-workers. Communicate effectively (orally and written) with coworkers, employees of other departments, supervisors, and administration. Knowledge of quality control practices and requirements of UKAS, ISO 15189 CAP and other regulatory agencies. Working Conditions: Clinical Laboratory environment; exposure to blood borne pathogens, hazardous chemicals; must wear personal protective equipment including lab coat, gloves and completely closed footwear. Weekend rotation may be required.