At the Ellison Institute of Technology (EIT), we're on a mission to translate scientific discovery into real world impact. We bring together visionary scientists, technologists, engineers, researchers, educators and innovators to tackle humanity's greatest challenges in four transformative areas: Health, Medical Science & Generative Biology Food Security & Sustainable Agriculture Climate Change & Managing CO Artificial Intelligence & Robotics This is ambitious work - work that demands curiosity, courage, and a relentless drive to make a difference. At EIT, you'll join a community built on excellence, innovation, tenacity, trust, and collaboration, where bold ideas become real-world breakthroughs. Together, we push boundaries, embrace complexity, and create solutions to scale ideas from lab to society. Explore more at . Welcome to the Pathogen Project Within this ecosystem, the Pathogen Mission exemplifies EIT's commitment to transformative science. It aims to revolutionise the diagnosis and treatment of infectious diseases by leveraging whole genome sequencing (WGS)-based metagenomic and pathogen specific analytical tools. This remit includes the development of a decentralised, sample to answer sequencing diagnostic platform for infectious diseases, enabling rapid and accurate analysis of patient samples without prior assumptions. Supported by Oracle Inc.'s cloud computing scale and security infrastructure, the Pathogen Mission is progressing towards certified diagnostic products for deployment in laboratories, hospitals, and public health organisations worldwide. Your Role We are seeking a Scientist or Senior Scientist with a strong interest in method development to join our growing Applications team, focused on advancing sequencing based diagnostics. In this role, you will contribute to the design and optimisation of novel targeted and semi targeted approaches for the rapid sequencing of clinically relevant pathogens. This laboratory based position encompasses end to end experimental workflows, including sample preparation, target enrichment and amplification, library preparation, and sequencing. You will support the development of strategies for comprehensive, high sensitivity sequencing across a large number of targets, using approaches such as targeted amplification, hybridisation, and related techniques. The role encourages creative problem solving, with opportunities to propose, explore, and evaluate new ideas. You will work collaboratively within a multidisciplinary team of microbiologists, molecular biologists, engineers, and data scientists to develop assays for integration into an automated, device based platform. Drawing on your experience, you will help define experimental strategies, design and execute studies, and contribute to advancing the application of sequencing technologies in pathogen detection and related areas. Key Responsibilities Design, develop, and optimise end to end sequencing assays (targeted and semi targeted) Execute experiments, analyse and interpret data, and contribute ideas for improvement Troubleshoot complex technical challenges across a range of sample types Maintain clear documentation to support reproducibility of experimental work Collaborate closely with colleagues across disciplines to progress shared goals Contribute to scientific discussions and decision making as projects evolve Essential Knowledge, Skills, and Experience PhD in molecular biology, microbiology, genomics, biochemistry or a related field Experience using molecular biology techniques (e.g. PCR, RT PCR, nucleic acid extraction, library preparation) Experience developing and optimising PCRs and/or related experimental workflows Ability to troubleshoot experimental challenges and adapt methods as needed Experience with DNA/RNA sequencing data Strong experimental design and data interpretation skills Good organisation, record keeping and communication skills Desirable We recognise that strong candidates may not meet every criterion below. Experience in any of the following would be beneficial: Multiplex PCR assay development, particularly for sequencing applications Enrichment or capture methods for pathogens or pathogen derived nucleic acids Work with bacteria, fungi, viruses, or other pathogens Handling clinical samples RNA based workflows (e.g. transcriptomics, viral genomics) Background in virology Exposure to metagenomics workflows Biochemistry knowledge relevant to assay development (e.g. enzyme optimisation, reaction conditions, assay development) Key Attributes Scientific and Technical Enjoys exploring new ideas and approaches to experimental challenges Curious and motivated to solve complex problems Able to balance scientific rigour with speed and pragmatism Working Style and Collaboration Takes ownership of work while valuing collaboration and shared success Proactive and supportive team member, with a willingness to contribute beyond immediate responsibilities Comfortable working in a dynamic research environment, with support from colleagues Our Benefits Salary: Competitive + travel allowance + bonus Enhanced holiday pay Pension Life Assurance Income Protection Private Medical Insurance Hospital Cash Plan Therapy Services Perk Box Electric Car Scheme Working Together - What It Involves You must have the right to work permanently in the UK with a willingness to travel as necessary. In certain cases, we can consider sponsorship, and this will be assessed on a case by case basis. For this role we would expect someone to be fully on site in Oxford You will live in, or within easy commuting distance of, Oxford (or be willing to relocate).
May 01, 2026
Full time
At the Ellison Institute of Technology (EIT), we're on a mission to translate scientific discovery into real world impact. We bring together visionary scientists, technologists, engineers, researchers, educators and innovators to tackle humanity's greatest challenges in four transformative areas: Health, Medical Science & Generative Biology Food Security & Sustainable Agriculture Climate Change & Managing CO Artificial Intelligence & Robotics This is ambitious work - work that demands curiosity, courage, and a relentless drive to make a difference. At EIT, you'll join a community built on excellence, innovation, tenacity, trust, and collaboration, where bold ideas become real-world breakthroughs. Together, we push boundaries, embrace complexity, and create solutions to scale ideas from lab to society. Explore more at . Welcome to the Pathogen Project Within this ecosystem, the Pathogen Mission exemplifies EIT's commitment to transformative science. It aims to revolutionise the diagnosis and treatment of infectious diseases by leveraging whole genome sequencing (WGS)-based metagenomic and pathogen specific analytical tools. This remit includes the development of a decentralised, sample to answer sequencing diagnostic platform for infectious diseases, enabling rapid and accurate analysis of patient samples without prior assumptions. Supported by Oracle Inc.'s cloud computing scale and security infrastructure, the Pathogen Mission is progressing towards certified diagnostic products for deployment in laboratories, hospitals, and public health organisations worldwide. Your Role We are seeking a Scientist or Senior Scientist with a strong interest in method development to join our growing Applications team, focused on advancing sequencing based diagnostics. In this role, you will contribute to the design and optimisation of novel targeted and semi targeted approaches for the rapid sequencing of clinically relevant pathogens. This laboratory based position encompasses end to end experimental workflows, including sample preparation, target enrichment and amplification, library preparation, and sequencing. You will support the development of strategies for comprehensive, high sensitivity sequencing across a large number of targets, using approaches such as targeted amplification, hybridisation, and related techniques. The role encourages creative problem solving, with opportunities to propose, explore, and evaluate new ideas. You will work collaboratively within a multidisciplinary team of microbiologists, molecular biologists, engineers, and data scientists to develop assays for integration into an automated, device based platform. Drawing on your experience, you will help define experimental strategies, design and execute studies, and contribute to advancing the application of sequencing technologies in pathogen detection and related areas. Key Responsibilities Design, develop, and optimise end to end sequencing assays (targeted and semi targeted) Execute experiments, analyse and interpret data, and contribute ideas for improvement Troubleshoot complex technical challenges across a range of sample types Maintain clear documentation to support reproducibility of experimental work Collaborate closely with colleagues across disciplines to progress shared goals Contribute to scientific discussions and decision making as projects evolve Essential Knowledge, Skills, and Experience PhD in molecular biology, microbiology, genomics, biochemistry or a related field Experience using molecular biology techniques (e.g. PCR, RT PCR, nucleic acid extraction, library preparation) Experience developing and optimising PCRs and/or related experimental workflows Ability to troubleshoot experimental challenges and adapt methods as needed Experience with DNA/RNA sequencing data Strong experimental design and data interpretation skills Good organisation, record keeping and communication skills Desirable We recognise that strong candidates may not meet every criterion below. Experience in any of the following would be beneficial: Multiplex PCR assay development, particularly for sequencing applications Enrichment or capture methods for pathogens or pathogen derived nucleic acids Work with bacteria, fungi, viruses, or other pathogens Handling clinical samples RNA based workflows (e.g. transcriptomics, viral genomics) Background in virology Exposure to metagenomics workflows Biochemistry knowledge relevant to assay development (e.g. enzyme optimisation, reaction conditions, assay development) Key Attributes Scientific and Technical Enjoys exploring new ideas and approaches to experimental challenges Curious and motivated to solve complex problems Able to balance scientific rigour with speed and pragmatism Working Style and Collaboration Takes ownership of work while valuing collaboration and shared success Proactive and supportive team member, with a willingness to contribute beyond immediate responsibilities Comfortable working in a dynamic research environment, with support from colleagues Our Benefits Salary: Competitive + travel allowance + bonus Enhanced holiday pay Pension Life Assurance Income Protection Private Medical Insurance Hospital Cash Plan Therapy Services Perk Box Electric Car Scheme Working Together - What It Involves You must have the right to work permanently in the UK with a willingness to travel as necessary. In certain cases, we can consider sponsorship, and this will be assessed on a case by case basis. For this role we would expect someone to be fully on site in Oxford You will live in, or within easy commuting distance of, Oxford (or be willing to relocate).
Overview At the Ellison Institute of Technology (EIT), we're on a mission to translate scientific discovery into real world impact. We bring together visionary scientists, technologists, engineers, researchers, educators and innovators to tackle humanity's greatest challenges in four transformative areas: Health, Medical Science & Generative Biology Food Security & Sustainable Agriculture Climate Change & Managing CO Artificial Intelligence & Robotics This is ambitious work - work that demands curiosity, courage, and a relentless drive to make a difference. At EIT, you'll join a community built on excellence, innovation, tenacity, trust, and collaboration, where bold ideas become real-world breakthroughs. Explore more at . Welcome to the Pathogen Project: Within this ecosystem, the Pathogen Project exemplifies EIT's dedication to ground-breaking science. It seeks to transform pathogen risk management, detection and response by leveraging Whole Genome Sequencing (WGS)-based metagenomic and pathogen-specific analytical tools. The goal is to power metagenomic devices using long-read sequencing technologies by building a comprehensive database of pathogen information to inform response. Enabled by Oracle Inc.'s cloud-computing scale and security, the Pathogen Project is advancing toward certified diagnostic tools for deployment in laboratories, hospitals, and public health organisations worldwide. Your Role: At EIT we are seeking an experienced and detailed orientated (Senior or Non Senior) Scientist with recognised expertise in developing computational methods and algorithms for genomic sequencing data analysis. This is an exciting opportunity to develop novel computational approaches for microbial data that will become part of our diagnostic products and thus help shape the future of infectious disease diagnostics. Reporting to the Lead Scientist in Computational Genomics, you will work closely with computational scientists, bioinformaticians, software engineers, and our database and data platform teams to deliver scientifically rigorous, scalable, and clinically relevant innovation in the microbial genomics space. Key Responsibilities: Design, develop and evaluate novel computational approaches in areas such as genome assembly, binning, and functional characterisation of genomes from metagenomic sequencing data Collaborate with scientists across EIT to apply the latest developments in AI/ML to real-world challenges in the pathogen space Work with bioinformaticians and software engineers to implement methods in scalable, reproducible, and modular workflows Perform rigorous benchmarking using public and internal datasets, and guide experimental validation efforts in collaboration with our wet-lab teams Communicate technical concepts to broad audiences and collaborate with interdisciplinary colleagues across the organisation Essential Knowledge, Skills and Experience: PhD or equivalent experience in bioinformatics, computational biology, computer science, or a related quantitative field Senior: At least 3 years of postdoctoral or industry experience developing computational methods for next-generation sequencing data Non-Senior: Hands-on experience developing computational methods for next-generation sequencing data Significant experience with bioinformatics methods such as efficient search and storage of DNA sequences, genome assembly, genome annotation, pangenomes, phylogenetics, and comparative genomics Solid understanding of data structures, algorithms, and statistical methods (e.g. De Bruijn graphs, hashing, Burrows-Wheeler transform, Bayesian methods, mixed models, dimensionality reduction, embeddings) Experience with machine learning in the context of biological data, particularly sequencing data Proficient in the use of command-line interfaces, low and high-level programming languages (e.g. Python, C, C++, Rust) and modern software development techniques (version control, CI/CD) Track record of scientific output and engagement with the computational genomics community Desirable Knowledge, Skills and Experience: Experience working with microbial genomes and shotgun metagenomics data Experience working with long-read sequencing data (ONT) Experience with bioinformatics workflow management (e.g. Nextflow) and cloud computing (e.g. OCI, AWS, GCP) Contributions to open-source bioinformatics software Previous experience mentoring or line-managing scientists (For Senior) Key Attributes: Strategic thinker with the ability to translate scientific insights into practical solutions Effective communicator and enthusiastic knowledge sharer across disciplines Rigorous and detail-oriented with a commitment to reproducibility and benchmarking Comfortable in a fast-paced, interdisciplinary environment and able to adapt to evolving priorities Collaborative ethos with the ability to work across teams and domains Our Benefits: Salary: Competitive + travel allowance + bonus Enhanced holiday + options to buy additional days Pension Life Assurance Income Protection Private Medical Insurance Hospital Cash Plan Therapy Services Perk Box Electric Car Scheme Childcare benefit Working Together - What It Involves: You must have the permanent right to work in the UK and be willing to travel when required. Given the specialised nature of this role, we can consider sponsorship for candidates who meet the expectations outlined in the job description. You will live in, or within easy commuting distance of, Oxford (or be willing to relocate).
May 01, 2026
Full time
Overview At the Ellison Institute of Technology (EIT), we're on a mission to translate scientific discovery into real world impact. We bring together visionary scientists, technologists, engineers, researchers, educators and innovators to tackle humanity's greatest challenges in four transformative areas: Health, Medical Science & Generative Biology Food Security & Sustainable Agriculture Climate Change & Managing CO Artificial Intelligence & Robotics This is ambitious work - work that demands curiosity, courage, and a relentless drive to make a difference. At EIT, you'll join a community built on excellence, innovation, tenacity, trust, and collaboration, where bold ideas become real-world breakthroughs. Explore more at . Welcome to the Pathogen Project: Within this ecosystem, the Pathogen Project exemplifies EIT's dedication to ground-breaking science. It seeks to transform pathogen risk management, detection and response by leveraging Whole Genome Sequencing (WGS)-based metagenomic and pathogen-specific analytical tools. The goal is to power metagenomic devices using long-read sequencing technologies by building a comprehensive database of pathogen information to inform response. Enabled by Oracle Inc.'s cloud-computing scale and security, the Pathogen Project is advancing toward certified diagnostic tools for deployment in laboratories, hospitals, and public health organisations worldwide. Your Role: At EIT we are seeking an experienced and detailed orientated (Senior or Non Senior) Scientist with recognised expertise in developing computational methods and algorithms for genomic sequencing data analysis. This is an exciting opportunity to develop novel computational approaches for microbial data that will become part of our diagnostic products and thus help shape the future of infectious disease diagnostics. Reporting to the Lead Scientist in Computational Genomics, you will work closely with computational scientists, bioinformaticians, software engineers, and our database and data platform teams to deliver scientifically rigorous, scalable, and clinically relevant innovation in the microbial genomics space. Key Responsibilities: Design, develop and evaluate novel computational approaches in areas such as genome assembly, binning, and functional characterisation of genomes from metagenomic sequencing data Collaborate with scientists across EIT to apply the latest developments in AI/ML to real-world challenges in the pathogen space Work with bioinformaticians and software engineers to implement methods in scalable, reproducible, and modular workflows Perform rigorous benchmarking using public and internal datasets, and guide experimental validation efforts in collaboration with our wet-lab teams Communicate technical concepts to broad audiences and collaborate with interdisciplinary colleagues across the organisation Essential Knowledge, Skills and Experience: PhD or equivalent experience in bioinformatics, computational biology, computer science, or a related quantitative field Senior: At least 3 years of postdoctoral or industry experience developing computational methods for next-generation sequencing data Non-Senior: Hands-on experience developing computational methods for next-generation sequencing data Significant experience with bioinformatics methods such as efficient search and storage of DNA sequences, genome assembly, genome annotation, pangenomes, phylogenetics, and comparative genomics Solid understanding of data structures, algorithms, and statistical methods (e.g. De Bruijn graphs, hashing, Burrows-Wheeler transform, Bayesian methods, mixed models, dimensionality reduction, embeddings) Experience with machine learning in the context of biological data, particularly sequencing data Proficient in the use of command-line interfaces, low and high-level programming languages (e.g. Python, C, C++, Rust) and modern software development techniques (version control, CI/CD) Track record of scientific output and engagement with the computational genomics community Desirable Knowledge, Skills and Experience: Experience working with microbial genomes and shotgun metagenomics data Experience working with long-read sequencing data (ONT) Experience with bioinformatics workflow management (e.g. Nextflow) and cloud computing (e.g. OCI, AWS, GCP) Contributions to open-source bioinformatics software Previous experience mentoring or line-managing scientists (For Senior) Key Attributes: Strategic thinker with the ability to translate scientific insights into practical solutions Effective communicator and enthusiastic knowledge sharer across disciplines Rigorous and detail-oriented with a commitment to reproducibility and benchmarking Comfortable in a fast-paced, interdisciplinary environment and able to adapt to evolving priorities Collaborative ethos with the ability to work across teams and domains Our Benefits: Salary: Competitive + travel allowance + bonus Enhanced holiday + options to buy additional days Pension Life Assurance Income Protection Private Medical Insurance Hospital Cash Plan Therapy Services Perk Box Electric Car Scheme Childcare benefit Working Together - What It Involves: You must have the permanent right to work in the UK and be willing to travel when required. Given the specialised nature of this role, we can consider sponsorship for candidates who meet the expectations outlined in the job description. You will live in, or within easy commuting distance of, Oxford (or be willing to relocate).
Hours per week 37 Project Title: Gut microbial colonization and adaptation to the human host. Months Duration: 24 Job Description Applications are invited for a Research Scientist to join the Laboratory of Prof Hildebrand in the Food, Microbes and Health programme at Quadram Institute Bioscience (QIB), Norwich, UK. The project will investigate how bacterial genomes evolve in closely related family members, focusing on adaptation through genetic mutation and DNA modification using 3rd generation DNA sequencing from hundreds of faecal metagenomes. Main Purpose of the Job The ideal candidate will have experience working with metagenomic data, understanding the gut ecosystem, and knowledge of bacterial evolution. Expertise in bioinformatics, cohort management, population genetics, or comparative genomics is highly desirable. The role involves quantifying adaptive processes that microbial strains undergo over short and long time spans, analysing genome plasticity via classical bioinformatics, and tracking DNA modifications across metagenomes. Key Relationships The post holder will work closely with group members, line manager Dr Fal k Hildebrand (Group Leader), and key collaborators. Supervision of junior members and representation at trainings are expected. Direct access to PacBio/ONT, Hi C and single cell sequencing facilities and the UK's largest HPC cluster at the NRP is provided. Main Activities & Responsibilities 35%: Analyse pro and eukaryotic MAGs from gut metagenomes, their community structure and functional potential. 35%: Investigate microbial adaptation in time series metagenomes using population genetics. Develop analytical workflows to integrate DNA mutations and modifications. 20%: Cohort related tasks on the established cohort (logistics, recruitment, ethics). 5%: Support the group with outreach, student supervision, and grant writing. 5%: Other duties as agreed with the line manager, such as contributing to institute committees. Education & Qualifications Requirement: PhD in Bioinformatics, Population Genetics, Ecology or Microbiology, or equivalent experience - essential. Specialist Knowledge & Skills Programming skills (C++, Perl, Python or R) - essential. Ability to work independently on research projects - essential. Initiative, desire to learn, innovate and step outside comfort zone - essential. Problem solving and troubleshooting - essential. DNA sequencing related bioinformatics - essential. Proven track record of relevant research output - essential. Lab member supervision experience - essential. Grant writing - essential. Metagenomics or population genetics experience - desirable. Previous cohort supervision or creation - desirable. Experience with DNA mutations or modifications (bioinformatics) - desirable. Interpersonal & Communication Skills Excellent written and oral communication - essential. Promotes and strives for continuous improvement - essential. Excellent interpersonal skills; ability to work alone and as part of a team - essential. Reliable and conscientious - essential. Additional Requirements Attention to detail - essential. Promotes equality and values diversity - essential. Will embrace the expected values and behaviours of all staff - essential. Willingness to work outside standard hours when required - essential. Willingness to undertake necessary training for the role - essential. The closing date for applications will be 17 May 2026. Interviews are planned for the week commencing 1 June 2026. We are committed to equal opportunities and welcome applications from all sectors of society. The Institute supports equality of opportunity within the workplace and expects all employees to share and display these values. To support our commitment, we have a range of family, faith and diversity friendly working arrangements to help all staff achieve excellence in their area of work. As a Disability Confident employer, we guarantee to offer an interview to all disabled applicants who meet the essential criteria for this vacancy. The Quadram Institute Bioscience is a registered charity (No. ) and is an Equal Opportunities Employer.
Apr 27, 2026
Full time
Hours per week 37 Project Title: Gut microbial colonization and adaptation to the human host. Months Duration: 24 Job Description Applications are invited for a Research Scientist to join the Laboratory of Prof Hildebrand in the Food, Microbes and Health programme at Quadram Institute Bioscience (QIB), Norwich, UK. The project will investigate how bacterial genomes evolve in closely related family members, focusing on adaptation through genetic mutation and DNA modification using 3rd generation DNA sequencing from hundreds of faecal metagenomes. Main Purpose of the Job The ideal candidate will have experience working with metagenomic data, understanding the gut ecosystem, and knowledge of bacterial evolution. Expertise in bioinformatics, cohort management, population genetics, or comparative genomics is highly desirable. The role involves quantifying adaptive processes that microbial strains undergo over short and long time spans, analysing genome plasticity via classical bioinformatics, and tracking DNA modifications across metagenomes. Key Relationships The post holder will work closely with group members, line manager Dr Fal k Hildebrand (Group Leader), and key collaborators. Supervision of junior members and representation at trainings are expected. Direct access to PacBio/ONT, Hi C and single cell sequencing facilities and the UK's largest HPC cluster at the NRP is provided. Main Activities & Responsibilities 35%: Analyse pro and eukaryotic MAGs from gut metagenomes, their community structure and functional potential. 35%: Investigate microbial adaptation in time series metagenomes using population genetics. Develop analytical workflows to integrate DNA mutations and modifications. 20%: Cohort related tasks on the established cohort (logistics, recruitment, ethics). 5%: Support the group with outreach, student supervision, and grant writing. 5%: Other duties as agreed with the line manager, such as contributing to institute committees. Education & Qualifications Requirement: PhD in Bioinformatics, Population Genetics, Ecology or Microbiology, or equivalent experience - essential. Specialist Knowledge & Skills Programming skills (C++, Perl, Python or R) - essential. Ability to work independently on research projects - essential. Initiative, desire to learn, innovate and step outside comfort zone - essential. Problem solving and troubleshooting - essential. DNA sequencing related bioinformatics - essential. Proven track record of relevant research output - essential. Lab member supervision experience - essential. Grant writing - essential. Metagenomics or population genetics experience - desirable. Previous cohort supervision or creation - desirable. Experience with DNA mutations or modifications (bioinformatics) - desirable. Interpersonal & Communication Skills Excellent written and oral communication - essential. Promotes and strives for continuous improvement - essential. Excellent interpersonal skills; ability to work alone and as part of a team - essential. Reliable and conscientious - essential. Additional Requirements Attention to detail - essential. Promotes equality and values diversity - essential. Will embrace the expected values and behaviours of all staff - essential. Willingness to work outside standard hours when required - essential. Willingness to undertake necessary training for the role - essential. The closing date for applications will be 17 May 2026. Interviews are planned for the week commencing 1 June 2026. We are committed to equal opportunities and welcome applications from all sectors of society. The Institute supports equality of opportunity within the workplace and expects all employees to share and display these values. To support our commitment, we have a range of family, faith and diversity friendly working arrangements to help all staff achieve excellence in their area of work. As a Disability Confident employer, we guarantee to offer an interview to all disabled applicants who meet the essential criteria for this vacancy. The Quadram Institute Bioscience is a registered charity (No. ) and is an Equal Opportunities Employer.
A leading research institute in Norwich is offering a Postdoctoral Scientist position to investigate bacterial genome evolution in relation to the human microbiome. The position requires a PhD in a relevant field, with skills in metagenomics, statistics, and programming. The role is full-time on a 24-month contract, with a salary range of £37,500 to £43,350 per annum. This opportunity is ideal for individuals passionate about research and offers a supportive environment for career development.
Apr 27, 2026
Full time
A leading research institute in Norwich is offering a Postdoctoral Scientist position to investigate bacterial genome evolution in relation to the human microbiome. The position requires a PhD in a relevant field, with skills in metagenomics, statistics, and programming. The role is full-time on a 24-month contract, with a salary range of £37,500 to £43,350 per annum. This opportunity is ideal for individuals passionate about research and offers a supportive environment for career development.
A leading research institute in Norwich is seeking a Postdoctoral Scientist to investigate bacterial genome evolution related to family members. The researcher will use third-generation DNA sequencing to explore gut microbial colonization. The ideal candidate should hold a PhD in biology or a related field and have experience in scientific research, programming, and statistics. Salary ranges from £37,500 to £43,350 per annum for a contract of 24 months.
Apr 27, 2026
Full time
A leading research institute in Norwich is seeking a Postdoctoral Scientist to investigate bacterial genome evolution related to family members. The researcher will use third-generation DNA sequencing to explore gut microbial colonization. The ideal candidate should hold a PhD in biology or a related field and have experience in scientific research, programming, and statistics. Salary ranges from £37,500 to £43,350 per annum for a contract of 24 months.
A notable bioscience research institute in Norwich is seeking a Research Scientist to focus on gut microbial colonization and adaptation. This role requires a PhD in Bioinformatics, Population Genetics, Ecology, or Microbiology, along with essential programming skills in C++, Perl, Python, or R. The position involves analyzing genomic data and tracking DNA modifications, contributing to a leading research project with access to advanced sequencing technologies. The application deadline is 17 May 2026, with interviews in early June.
Apr 27, 2026
Full time
A notable bioscience research institute in Norwich is seeking a Research Scientist to focus on gut microbial colonization and adaptation. This role requires a PhD in Bioinformatics, Population Genetics, Ecology, or Microbiology, along with essential programming skills in C++, Perl, Python, or R. The position involves analyzing genomic data and tracking DNA modifications, contributing to a leading research project with access to advanced sequencing technologies. The application deadline is 17 May 2026, with interviews in early June.
Organisation/Company Quadram Institute Bioscience Department Biochemistry and Metabolism Research Field Biological sciences " Biology Researcher Profile First Stage Researcher (R1) Positions PhD Positions Application Deadline 17 May 2026 - 23:59 (Europe/London) Country United Kingdom Type of Contract Temporary Job Status Full-time Hours Per Week 37 Is the job funded through the EU Research Framework Programme? Not funded by a EU programme Is the Job related to staff position within a Research Infrastructure? No Offer Description Applications are invited for a Postdoctoral Scientist to join the laboratory of Prof Falk Hildebrand at Quadram Institute Bioscience (QIB), Norwich, UK. Background: The human microbiome is shared among family members in all life stages (doi:10.1016/j.chom.2021.05.008). To investigate potential mechanisms and the impact on bacterial evolution, we created the PEARL-AGE cohort in Norwich ( ), collecting samples from multi-generational families longitudinally, as well as biodata. The role: The project will investigate how bacterial genomes evolve in closely related family members. Specifically, adaptation to individuals through genetic mutation and DNA modification will be investigated, relying on 3rd generation DNA sequencing from hundreds of faecal metagenomes. The project will investigate the following questions: Which gut microbes are most prone to colonise family members, and what are likely genetic determinants? How can some bacteria persist for decades in the same host? Are there unique genetic adaptations to each host or each host family? The environment: The Hildebrand group ( ) uses metagenomics to research the diversity, interactions, and evolution of microbial communities using custom software solutions. The group is jointly based at the Quadram Institute Bioscience and Earlham Institute, to bridge data and life science, developing software such as LotuS3 and MATAFILER and pushing the limits of high-resolution metagenomics ( ). The ideal candidate: The ideal applicant holds a PhD (or equivalent) in biology, bioinformatics, computer science or a related discipline, with a background and/or interest in at least one of the following subjects: Microbiomes & biodiversity Metagenomics & patient cohorts Ecology & evolution Experience in conducting scientific experiments independently, writing papers, scientific presentations is required. Skills in statistics, programming, working with human cohorts, comparative genome analysis, determining genetic adaptation, analysing DNA modifications (methylation), grant writing are beneficial. Specialised skills will be taught and developed through mentorship and collaborations. Additional information: Salary on appointment will be within the range £37,500 to £43,350 per annum depending on qualifications and experience. This is a full-time post for a contract of 24 months. For further information and details of how to apply, please visit our website or contact the Human Resources team on or quoting reference . This role meets the criteria for a visa application, and we encourage all qualified candidates to apply. Please contact the Human Resources Team if you have any questions regarding your application or visa options. We are committed to equal opportunities and welcome applications from all sectors of society. The Institute supports equality of opportunity within the workplace and expects all employees to share and display these values. To support our commitment, we have a range of family, faith and diversity friendly working arrangements to help all staff achieve excellence in their area of work. As a Disability Confident employer, we guarantee to offer an interview to all disabled applicants who meet the essential criteria for this vacancy. About the Quadram Institute: The Quadram Institute is located on the Norwich Research Park, one of Europe's largest single-site concentrations of research in food, genomics, and health. The Park hosts four BBSRC institutes (including Quadram), around 17,000 students, 3,000 researchers and clinicians, and more than 115 companies. Its researchers are internationally recognized, with 10 scientists ranked among the top 1% of the world's most highly cited, including Prof Hildebrand (2024 & 2025). Norwich is regularly ranked among the top UK cities to live in, known for its historic city centre and vibrant food and coffee culture. In 2026 it was named the "best UK city to live in" (). Closing date for applications: 17 May 2026. Interviews are planned for week commencing 1 June 2026. Quadram Institute Bioscience is a registered charity (No. ) and is an Equal Opportunities Employer.
Apr 27, 2026
Full time
Organisation/Company Quadram Institute Bioscience Department Biochemistry and Metabolism Research Field Biological sciences " Biology Researcher Profile First Stage Researcher (R1) Positions PhD Positions Application Deadline 17 May 2026 - 23:59 (Europe/London) Country United Kingdom Type of Contract Temporary Job Status Full-time Hours Per Week 37 Is the job funded through the EU Research Framework Programme? Not funded by a EU programme Is the Job related to staff position within a Research Infrastructure? No Offer Description Applications are invited for a Postdoctoral Scientist to join the laboratory of Prof Falk Hildebrand at Quadram Institute Bioscience (QIB), Norwich, UK. Background: The human microbiome is shared among family members in all life stages (doi:10.1016/j.chom.2021.05.008). To investigate potential mechanisms and the impact on bacterial evolution, we created the PEARL-AGE cohort in Norwich ( ), collecting samples from multi-generational families longitudinally, as well as biodata. The role: The project will investigate how bacterial genomes evolve in closely related family members. Specifically, adaptation to individuals through genetic mutation and DNA modification will be investigated, relying on 3rd generation DNA sequencing from hundreds of faecal metagenomes. The project will investigate the following questions: Which gut microbes are most prone to colonise family members, and what are likely genetic determinants? How can some bacteria persist for decades in the same host? Are there unique genetic adaptations to each host or each host family? The environment: The Hildebrand group ( ) uses metagenomics to research the diversity, interactions, and evolution of microbial communities using custom software solutions. The group is jointly based at the Quadram Institute Bioscience and Earlham Institute, to bridge data and life science, developing software such as LotuS3 and MATAFILER and pushing the limits of high-resolution metagenomics ( ). The ideal candidate: The ideal applicant holds a PhD (or equivalent) in biology, bioinformatics, computer science or a related discipline, with a background and/or interest in at least one of the following subjects: Microbiomes & biodiversity Metagenomics & patient cohorts Ecology & evolution Experience in conducting scientific experiments independently, writing papers, scientific presentations is required. Skills in statistics, programming, working with human cohorts, comparative genome analysis, determining genetic adaptation, analysing DNA modifications (methylation), grant writing are beneficial. Specialised skills will be taught and developed through mentorship and collaborations. Additional information: Salary on appointment will be within the range £37,500 to £43,350 per annum depending on qualifications and experience. This is a full-time post for a contract of 24 months. For further information and details of how to apply, please visit our website or contact the Human Resources team on or quoting reference . This role meets the criteria for a visa application, and we encourage all qualified candidates to apply. Please contact the Human Resources Team if you have any questions regarding your application or visa options. We are committed to equal opportunities and welcome applications from all sectors of society. The Institute supports equality of opportunity within the workplace and expects all employees to share and display these values. To support our commitment, we have a range of family, faith and diversity friendly working arrangements to help all staff achieve excellence in their area of work. As a Disability Confident employer, we guarantee to offer an interview to all disabled applicants who meet the essential criteria for this vacancy. About the Quadram Institute: The Quadram Institute is located on the Norwich Research Park, one of Europe's largest single-site concentrations of research in food, genomics, and health. The Park hosts four BBSRC institutes (including Quadram), around 17,000 students, 3,000 researchers and clinicians, and more than 115 companies. Its researchers are internationally recognized, with 10 scientists ranked among the top 1% of the world's most highly cited, including Prof Hildebrand (2024 & 2025). Norwich is regularly ranked among the top UK cities to live in, known for its historic city centre and vibrant food and coffee culture. In 2026 it was named the "best UK city to live in" (). Closing date for applications: 17 May 2026. Interviews are planned for week commencing 1 June 2026. Quadram Institute Bioscience is a registered charity (No. ) and is an Equal Opportunities Employer.
Food, Microbiome & Health, Quadram Institute Bioscience Applications are invited for a Postdoctoral Scientist position in the Hildebrand group at the Quadram Institute Bioscience (QIB), Norwich, UK. Background: Microbial fermentation of plant-based foods is increasingly used to recreate the taste, texture, and nutritional qualities of meat, while improving environmental sustainability. Optimizing the production of plant-based foods and ensuring consumer acceptance remain important challenges, further complicated by new and diverse fermentation approaches. The role: In the FlavourFerm consortium, partners are developing novel fermented plant-based foods. This research position will investigate how these foods influence the human gut microbiome and offer potential benefits to host health. Taste and texture of these foods will be predicted from microbial fermentation consortia. Specifically, microbes will be identified that affect fermentation outcomes. Building on previous work from the host group, we will develop machine learning tools to model microbial communities and their impact. In the longer term, this research will support the development of human-centric fermented foods that are safe, appealing, and environmentally sustainable. The environment: The successful applicant will work within the Hildebrand and Traka groups, integrated in the H2020 international FlavourFerm consortium. Prof Hildebrand studies the diversity, interactions, and evolution of microbial communities using high resolution metagenomics and custom software tools. The group is jointly based at QIB and the Earlham Institute developing widely used bioinformatic tools. Dr Traka leads the UK national resource Food & Nutrition National Bioscience Research Infrastructure, focused on automated food categorization using AI. FlavourFerm combines microbiologists, machine learning and food scientists, to develop the next generation of healthy and sustainable nutrition. The project requires close collaborations across Europe; attendance and participation in workshops and consortium meetings is required. The ideal candidate: holds a PhD (or equivalent) in biology, bioinformatics, computer science or a related discipline, being experienced in bioinformatics, (meta)genomic data, and microbiology. Knowledge in AI, machine learning, microbial pathogens, microbiology of fermentation, comparative genomics and analysing microbial communities will be of benefit. Specialized skills will be taught and developed through mentorship and collaborations. Salary on appointment will be within the range £37,500 to £43,350 per annum depending on qualifications and experience. This is a full time post until 30 April 2028. Closing date for applications will be 17 May 2026. Interviews are planned for week commencing 1st June 2026. We are committed to equal opportunities and welcome applications from all sectors of society. The Institute supports equality of opportunity within the workplace and expects all employees to share and display these values. The Institute is an Equality Confident employer.
Apr 27, 2026
Full time
Food, Microbiome & Health, Quadram Institute Bioscience Applications are invited for a Postdoctoral Scientist position in the Hildebrand group at the Quadram Institute Bioscience (QIB), Norwich, UK. Background: Microbial fermentation of plant-based foods is increasingly used to recreate the taste, texture, and nutritional qualities of meat, while improving environmental sustainability. Optimizing the production of plant-based foods and ensuring consumer acceptance remain important challenges, further complicated by new and diverse fermentation approaches. The role: In the FlavourFerm consortium, partners are developing novel fermented plant-based foods. This research position will investigate how these foods influence the human gut microbiome and offer potential benefits to host health. Taste and texture of these foods will be predicted from microbial fermentation consortia. Specifically, microbes will be identified that affect fermentation outcomes. Building on previous work from the host group, we will develop machine learning tools to model microbial communities and their impact. In the longer term, this research will support the development of human-centric fermented foods that are safe, appealing, and environmentally sustainable. The environment: The successful applicant will work within the Hildebrand and Traka groups, integrated in the H2020 international FlavourFerm consortium. Prof Hildebrand studies the diversity, interactions, and evolution of microbial communities using high resolution metagenomics and custom software tools. The group is jointly based at QIB and the Earlham Institute developing widely used bioinformatic tools. Dr Traka leads the UK national resource Food & Nutrition National Bioscience Research Infrastructure, focused on automated food categorization using AI. FlavourFerm combines microbiologists, machine learning and food scientists, to develop the next generation of healthy and sustainable nutrition. The project requires close collaborations across Europe; attendance and participation in workshops and consortium meetings is required. The ideal candidate: holds a PhD (or equivalent) in biology, bioinformatics, computer science or a related discipline, being experienced in bioinformatics, (meta)genomic data, and microbiology. Knowledge in AI, machine learning, microbial pathogens, microbiology of fermentation, comparative genomics and analysing microbial communities will be of benefit. Specialized skills will be taught and developed through mentorship and collaborations. Salary on appointment will be within the range £37,500 to £43,350 per annum depending on qualifications and experience. This is a full time post until 30 April 2028. Closing date for applications will be 17 May 2026. Interviews are planned for week commencing 1st June 2026. We are committed to equal opportunities and welcome applications from all sectors of society. The Institute supports equality of opportunity within the workplace and expects all employees to share and display these values. The Institute is an Equality Confident employer.
Job Description Applications are invited for a Research Scientist to join the Laboratory of Prof Hildebrand in the Food, Microbes and Health programme at Quadram Institute Bioscience (QIB), Norwich, UK. Main Purpose of the Job Investigate the impact of fermented, plant based foods on the human gut microbiome and evaluate potential pathogenic interactions with the host to develop new standards for food safety. Analyse taste and texture of fermented foods from fermentation consortia, predict these attributes from microbial community data, and identify microbial species that influence fermentation outcomes. Develop next generation microbial community modelling tools using AI, building on earlier work in the group (doi:10.1016/j.chom.2023.05.024; doi:10.1093/nar/gkaf1388). Work as part of the inter disciplinary FlavourFerm consortium, collaborating with food scientists, machine learning experts, and microbiologists across Europe. Key Relationships Collaborate closely with Prof Falk Hildebrand, Dr Maria Traka, the Traka group at QIB, Syddansk University (Denmark) and the Austrian Institute of Technology, and other FlavourFerm partners. Supervise junior group members and represent the group at training events and consortium meetings. Main Activities & Responsibilities Prepare and analyse metagenomes from in vitro gut models using high resolution, genome resolved metagenomics. Develop statistical frameworks to describe microbiome perturbations (e.g., NMF, network analysis). Apply machine learning approaches to predict the impact of microbes on food fermentation performance. Support the group with outreach, student supervision, and grant writing. Represent the group at collaborative meetings and in line manager discussions. Education & Qualifications PhD in Bioinformatics, Population Genetics, Ecology, Microbiology, or equivalent. Specialist Knowledge & Skills Programming skills in Python, R, or Bash. Experience working independently on research projects. Strong initiative, willingness to learn, and ability to innovate. Proficient troubleshooting and problem solving skills. Machine learning/AI expertise. Proven track record of research output at the appropriate level. Familiarity with DNA sequencing bioinformatics. Experience in metagenomics (high resolution, MAGs). Desirable: experience with fermentation microbiomes, grant writing, and supervising lab members. Interpersonal & Communication Skills Excellent written and oral communication skills. Strong interpersonal skills, capable of working both independently and as part of a team. Reliable, conscientious, and promoting continuous improvement. Additional Requirements Attention to detail. Commitment to equality, diversity, and inclusion. Willingness to work outside standard hours when required. Openness to training needed for the role. About Quadram Institute Bioscience QIB lies within the Norwich Research Park, a leading hub for food, genomics, and health research in Europe. The institute collaborates with industry, clinical services, and academia to promote scientific excellence and innovation. Closing Information Salary: £37,500-£43,350 per annum, depending on qualifications and experience. The position is full time until 30 April 2028, with a closing date for applications on 17 May 2026. The Institute is a registered charity (No. ) and an Equal Opportunities Employer. For more information about the role or visa arrangements, please contact the Human Resources Team.
Apr 26, 2026
Full time
Job Description Applications are invited for a Research Scientist to join the Laboratory of Prof Hildebrand in the Food, Microbes and Health programme at Quadram Institute Bioscience (QIB), Norwich, UK. Main Purpose of the Job Investigate the impact of fermented, plant based foods on the human gut microbiome and evaluate potential pathogenic interactions with the host to develop new standards for food safety. Analyse taste and texture of fermented foods from fermentation consortia, predict these attributes from microbial community data, and identify microbial species that influence fermentation outcomes. Develop next generation microbial community modelling tools using AI, building on earlier work in the group (doi:10.1016/j.chom.2023.05.024; doi:10.1093/nar/gkaf1388). Work as part of the inter disciplinary FlavourFerm consortium, collaborating with food scientists, machine learning experts, and microbiologists across Europe. Key Relationships Collaborate closely with Prof Falk Hildebrand, Dr Maria Traka, the Traka group at QIB, Syddansk University (Denmark) and the Austrian Institute of Technology, and other FlavourFerm partners. Supervise junior group members and represent the group at training events and consortium meetings. Main Activities & Responsibilities Prepare and analyse metagenomes from in vitro gut models using high resolution, genome resolved metagenomics. Develop statistical frameworks to describe microbiome perturbations (e.g., NMF, network analysis). Apply machine learning approaches to predict the impact of microbes on food fermentation performance. Support the group with outreach, student supervision, and grant writing. Represent the group at collaborative meetings and in line manager discussions. Education & Qualifications PhD in Bioinformatics, Population Genetics, Ecology, Microbiology, or equivalent. Specialist Knowledge & Skills Programming skills in Python, R, or Bash. Experience working independently on research projects. Strong initiative, willingness to learn, and ability to innovate. Proficient troubleshooting and problem solving skills. Machine learning/AI expertise. Proven track record of research output at the appropriate level. Familiarity with DNA sequencing bioinformatics. Experience in metagenomics (high resolution, MAGs). Desirable: experience with fermentation microbiomes, grant writing, and supervising lab members. Interpersonal & Communication Skills Excellent written and oral communication skills. Strong interpersonal skills, capable of working both independently and as part of a team. Reliable, conscientious, and promoting continuous improvement. Additional Requirements Attention to detail. Commitment to equality, diversity, and inclusion. Willingness to work outside standard hours when required. Openness to training needed for the role. About Quadram Institute Bioscience QIB lies within the Norwich Research Park, a leading hub for food, genomics, and health research in Europe. The institute collaborates with industry, clinical services, and academia to promote scientific excellence and innovation. Closing Information Salary: £37,500-£43,350 per annum, depending on qualifications and experience. The position is full time until 30 April 2028, with a closing date for applications on 17 May 2026. The Institute is a registered charity (No. ) and an Equal Opportunities Employer. For more information about the role or visa arrangements, please contact the Human Resources Team.
We are seeking a highly motivated Research Scientist in Metaproteomics to join a collaborative team focused on developing next generation computational methods for microbiome and metaproteomics data analysis. The role is primarily computational, involving the analysis and interpretation of large scale metaproteomics datasets, pipeline development and integration with other omics, and close collaboration with experimental researchers. The post holder will work closely with a multidisciplinary group at the Quadram Institute, with access to state of the art metagenomics, metaproteomics and metabolomics infrastructure, and will design, implement and optimise computational pipelines to interpret microbiome function and its impact on host health, including AI assisted approaches. Key Relationships Work closely with Group Leader Kai Cheng, other group members, the Bioinformatics Team and the experimental metaproteomics team led by Prof. Daniel Figeys. Responsibilities Develop, implement and optimise computational pipelines for metaproteomics data analysis. Integrate metaproteomics data with other omics (metagenomics, metabolomics) to generate biological insights. Apply and adapt computational and AI based methods for peptide/protein identification, quantification, functional annotation and biological discovery. Perform large scale data management, curation and computational analyses using high performance computing resources. Prepare results, reports and manuscripts for publication and present findings at scientific meetings. Assist in the preparation of research proposals and grant applications. Support the profile and reputation of the institute through engagement activities. Ensure research is conducted in accordance with best practices, scientific integrity and relevant policies. Contribute to the smooth running of the group, including mentoring and training activities. Carry out other duties commensurate with the nature of the post, as agreed with the line manager. Education & Qualifications PhD in Proteomics, Bioinformatics, Computational Biology or a related field (essential). Specialist Knowledge & Skills Strong understanding of proteomics or metaproteomics principles. Experience in metaproteomics or proteomics data analysis (DDA/DIA MS). Ability to interpret omics data in a biological context, particularly microbiome related questions. Proficiency in programming/scripting (Python, R, or Java). Experience with computational workflows for large scale omics data. Knowledge of statistical methods for high dimensional data. Experience with machine learning or AI approaches in biology. Demonstrated ability to analyse and interpret proteomics/metaproteomics data. Proven record in scientific writing and publication. Experience developing or applying computational workflows. Experience presenting research at scientific meetings. Contributions to collaborative or open source projects. Desirable: experience in multi omics data integration. Desirable: familiarity with microbiome or clinical datasets. Desirable: experience supervising students or providing technical training. Interpersonal & Communication Skills Good interpersonal skills and ability to work as part of a team. Excellent communication skills, both written and oral. Strong organisational and time management skills. Ability to collaborate with internal and external stakeholders. Demonstrated ability to work independently, using initiative and applying problem solving skills. Ability to work to deadlines. Additional Requirements Attention to detail. Promotes equality and values diversity. Commitment to scientific integrity and best practices. Willingness to embrace the expected values and behaviours of all staff at the Institute, ensuring a great place to work. Eligible to present a positive image of self and the Institute, promoting its international reputation and public engagement aims. Ability to maintain confidentiality and security of information where appropriate. Willingness to undertake occasional travel (national and international) related to collaborations and conferences. Benefits & Salary Salary on appointment will be within the range £37,500 to £45,350 per annum depending on qualifications and experience. This is a full time post for a 24 month contract. The closing date for applications is 6 May 2026. As a Disability Confident employer we guarantee to offer an interview to all disabled applicants who meet the essential criteria for this vacancy. The Quadram Institute Bioscience is a registered charity (No. ) and is an Equal Opportunities Employer. This role meets the criteria for a visa application, and we encourage all qualified candidates to apply.
Apr 25, 2026
Full time
We are seeking a highly motivated Research Scientist in Metaproteomics to join a collaborative team focused on developing next generation computational methods for microbiome and metaproteomics data analysis. The role is primarily computational, involving the analysis and interpretation of large scale metaproteomics datasets, pipeline development and integration with other omics, and close collaboration with experimental researchers. The post holder will work closely with a multidisciplinary group at the Quadram Institute, with access to state of the art metagenomics, metaproteomics and metabolomics infrastructure, and will design, implement and optimise computational pipelines to interpret microbiome function and its impact on host health, including AI assisted approaches. Key Relationships Work closely with Group Leader Kai Cheng, other group members, the Bioinformatics Team and the experimental metaproteomics team led by Prof. Daniel Figeys. Responsibilities Develop, implement and optimise computational pipelines for metaproteomics data analysis. Integrate metaproteomics data with other omics (metagenomics, metabolomics) to generate biological insights. Apply and adapt computational and AI based methods for peptide/protein identification, quantification, functional annotation and biological discovery. Perform large scale data management, curation and computational analyses using high performance computing resources. Prepare results, reports and manuscripts for publication and present findings at scientific meetings. Assist in the preparation of research proposals and grant applications. Support the profile and reputation of the institute through engagement activities. Ensure research is conducted in accordance with best practices, scientific integrity and relevant policies. Contribute to the smooth running of the group, including mentoring and training activities. Carry out other duties commensurate with the nature of the post, as agreed with the line manager. Education & Qualifications PhD in Proteomics, Bioinformatics, Computational Biology or a related field (essential). Specialist Knowledge & Skills Strong understanding of proteomics or metaproteomics principles. Experience in metaproteomics or proteomics data analysis (DDA/DIA MS). Ability to interpret omics data in a biological context, particularly microbiome related questions. Proficiency in programming/scripting (Python, R, or Java). Experience with computational workflows for large scale omics data. Knowledge of statistical methods for high dimensional data. Experience with machine learning or AI approaches in biology. Demonstrated ability to analyse and interpret proteomics/metaproteomics data. Proven record in scientific writing and publication. Experience developing or applying computational workflows. Experience presenting research at scientific meetings. Contributions to collaborative or open source projects. Desirable: experience in multi omics data integration. Desirable: familiarity with microbiome or clinical datasets. Desirable: experience supervising students or providing technical training. Interpersonal & Communication Skills Good interpersonal skills and ability to work as part of a team. Excellent communication skills, both written and oral. Strong organisational and time management skills. Ability to collaborate with internal and external stakeholders. Demonstrated ability to work independently, using initiative and applying problem solving skills. Ability to work to deadlines. Additional Requirements Attention to detail. Promotes equality and values diversity. Commitment to scientific integrity and best practices. Willingness to embrace the expected values and behaviours of all staff at the Institute, ensuring a great place to work. Eligible to present a positive image of self and the Institute, promoting its international reputation and public engagement aims. Ability to maintain confidentiality and security of information where appropriate. Willingness to undertake occasional travel (national and international) related to collaborations and conferences. Benefits & Salary Salary on appointment will be within the range £37,500 to £45,350 per annum depending on qualifications and experience. This is a full time post for a 24 month contract. The closing date for applications is 6 May 2026. As a Disability Confident employer we guarantee to offer an interview to all disabled applicants who meet the essential criteria for this vacancy. The Quadram Institute Bioscience is a registered charity (No. ) and is an Equal Opportunities Employer. This role meets the criteria for a visa application, and we encourage all qualified candidates to apply.
Organisation/Company Quadram Institute Bioscience Department Biochemistry and Metabolism Research Field Biological sciences " Biology Researcher Profile First Stage Researcher (R1) Positions PhD Positions Application Deadline 17 May 2026 - 23:59 (Europe/London) Country United Kingdom Type of Contract Temporary Job Status Full-time Hours Per Week 37 Is the job funded through the EU Research Framework Programme? Not funded by a EU programme Is the Job related to staff position within a Research Infrastructure? No Offer Description Applications are invited for a Postdoctoral Scientist to join the laboratory of Prof Falk Hildebrand at Quadram Institute Bioscience (QIB), Norwich, UK. Background: The human microbiome is shared among family members in all life stages (doi:10.1016/j.chom.2021.05.008). To investigate potential mechanisms and the impact on bacterial evolution, we created the PEARL-AGE cohort in Norwich ( ), collecting samples from multi-generational families longitudinally, as well as biodata. The role: The project will investigate how bacterial genomes evolve in closely related family members. Specifically, adaptation to individuals through genetic mutation and DNA modification will be investigated, relying on 3rd generation DNA sequencing from hundreds of faecal metagenomes. The project will investigate the following questions: Which gut microbes are most prone to colonise family members, and what are likely genetic determinants? How can some bacteria persist for decades in the same host? Are there unique genetic adaptations to each host or each host family? The environment: The Hildebrand group ( ) uses metagenomics to research the diversity, interactions, and evolution of microbial communities using custom software solutions. The group is jointly based at the Quadram Institute Bioscience and Earlham Institute, to bridge data and life science, developing software such as LotuS3 and MATAFILER and pushing the limits of high-resolution metagenomics ( ). The ideal candidate: The ideal applicant holds a PhD (or equivalent) in biology, bioinformatics, computer science or a related discipline, with a background and/or interest in at least one of the following subjects: Microbiomes & biodiversity Metagenomics & patient cohorts Ecology & evolution Experience in conducting scientific experiments independently, writing papers, scientific presentations is required. Skills in statistics, programming, working with human cohorts, comparative genome analysis, determining genetic adaptation, analysing DNA modifications (methylation), grant writing are beneficial. Specialised skills will be taught and developed through mentorship and collaborations. Additional information: Salary on appointment will be within the range £37,500 to £43,350 per annum depending on qualifications and experience. This is a full-time post for a contract of 24 months. For further information and details of how to apply, please visit our website or contact the Human Resources team on or quoting reference . This role meets the criteria for a visa application, and we encourage all qualified candidates to apply. Please contact the Human Resources Team if you have any questions regarding your application or visa options. We are committed to equal opportunities and welcome applications from all sectors of society. The Institute supports equality of opportunity within the workplace and expects all employees to share and display these values. To support our commitment, we have a range of family, faith and diversity friendly working arrangements to help all staff achieve excellence in their area of work. As a Disability Confident employer, we guarantee to offer an interview to all disabled applicants who meet the essential criteria for this vacancy. About the Quadram Institute: The Quadram Institute is located on the Norwich Research Park, one of Europe's largest single-site concentrations of research in food, genomics, and health. The Park hosts four BBSRC institutes (including Quadram), around 17,000 students, 3,000 researchers and clinicians, and more than 115 companies. Its researchers are internationally recognized, with 10 scientists ranked among the top 1% of the world's most highly cited, including Prof Hildebrand (2024 & 2025). Norwich is regularly ranked among the top UK cities to live in, known for its historic city centre and vibrant food and coffee culture. In 2026 it was named the "best UK city to live in" (). Closing date for applications: 17 May 2026. Interviews are planned for week commencing 1 June 2026. Quadram Institute Bioscience is a registered charity (No. ) and is an Equal Opportunities Employer.
Apr 25, 2026
Full time
Organisation/Company Quadram Institute Bioscience Department Biochemistry and Metabolism Research Field Biological sciences " Biology Researcher Profile First Stage Researcher (R1) Positions PhD Positions Application Deadline 17 May 2026 - 23:59 (Europe/London) Country United Kingdom Type of Contract Temporary Job Status Full-time Hours Per Week 37 Is the job funded through the EU Research Framework Programme? Not funded by a EU programme Is the Job related to staff position within a Research Infrastructure? No Offer Description Applications are invited for a Postdoctoral Scientist to join the laboratory of Prof Falk Hildebrand at Quadram Institute Bioscience (QIB), Norwich, UK. Background: The human microbiome is shared among family members in all life stages (doi:10.1016/j.chom.2021.05.008). To investigate potential mechanisms and the impact on bacterial evolution, we created the PEARL-AGE cohort in Norwich ( ), collecting samples from multi-generational families longitudinally, as well as biodata. The role: The project will investigate how bacterial genomes evolve in closely related family members. Specifically, adaptation to individuals through genetic mutation and DNA modification will be investigated, relying on 3rd generation DNA sequencing from hundreds of faecal metagenomes. The project will investigate the following questions: Which gut microbes are most prone to colonise family members, and what are likely genetic determinants? How can some bacteria persist for decades in the same host? Are there unique genetic adaptations to each host or each host family? The environment: The Hildebrand group ( ) uses metagenomics to research the diversity, interactions, and evolution of microbial communities using custom software solutions. The group is jointly based at the Quadram Institute Bioscience and Earlham Institute, to bridge data and life science, developing software such as LotuS3 and MATAFILER and pushing the limits of high-resolution metagenomics ( ). The ideal candidate: The ideal applicant holds a PhD (or equivalent) in biology, bioinformatics, computer science or a related discipline, with a background and/or interest in at least one of the following subjects: Microbiomes & biodiversity Metagenomics & patient cohorts Ecology & evolution Experience in conducting scientific experiments independently, writing papers, scientific presentations is required. Skills in statistics, programming, working with human cohorts, comparative genome analysis, determining genetic adaptation, analysing DNA modifications (methylation), grant writing are beneficial. Specialised skills will be taught and developed through mentorship and collaborations. Additional information: Salary on appointment will be within the range £37,500 to £43,350 per annum depending on qualifications and experience. This is a full-time post for a contract of 24 months. For further information and details of how to apply, please visit our website or contact the Human Resources team on or quoting reference . This role meets the criteria for a visa application, and we encourage all qualified candidates to apply. Please contact the Human Resources Team if you have any questions regarding your application or visa options. We are committed to equal opportunities and welcome applications from all sectors of society. The Institute supports equality of opportunity within the workplace and expects all employees to share and display these values. To support our commitment, we have a range of family, faith and diversity friendly working arrangements to help all staff achieve excellence in their area of work. As a Disability Confident employer, we guarantee to offer an interview to all disabled applicants who meet the essential criteria for this vacancy. About the Quadram Institute: The Quadram Institute is located on the Norwich Research Park, one of Europe's largest single-site concentrations of research in food, genomics, and health. The Park hosts four BBSRC institutes (including Quadram), around 17,000 students, 3,000 researchers and clinicians, and more than 115 companies. Its researchers are internationally recognized, with 10 scientists ranked among the top 1% of the world's most highly cited, including Prof Hildebrand (2024 & 2025). Norwich is regularly ranked among the top UK cities to live in, known for its historic city centre and vibrant food and coffee culture. In 2026 it was named the "best UK city to live in" (). Closing date for applications: 17 May 2026. Interviews are planned for week commencing 1 June 2026. Quadram Institute Bioscience is a registered charity (No. ) and is an Equal Opportunities Employer.
