P2P
About Us GSR is crypto's capital markets partner, helping founders and institutions scale with confidence. With over a decade of specialized expertise, we deliver institutional-grade market making, OTC trading, and strategic venture capital to support growth at every stage. Our value goes beyond execution. We provide access to liquidity, real-time market intelligence, and strategic guidance shaped by years operating at the center of global crypto markets. We bridge the gap between traditional finance and digital assets, connecting teams with the capital, market access, and insights they need to build what's next. The Role This role sits at the heart of the employee experience at GSR, supporting the smooth running of HR operations and helping employees navigate key moments in their journey,from joining the business through to development and beyond. You'll work closely with both employees and managers, gaining exposure across a wide range of HR activities while building a strong foundation in how a high-performing, global organisation operates. Key Responsibilities Support the employee experience end-to-end Act as a first point of contact for all general HR queries, helping employees receive clear and timely support Manage all onboarding, offboarding, and background screening processes Play a key role in creating a smooth and positive experience for new joiners Keep HR operations running smoothly Maintain accurate employee data and HR systems including payroll-related updates and coordination Support key processes such as probation reviews and performance cycles Assist managers with day-to-day HR processes and questions Contribute to broader HR work Get involved in projects such as engagement surveys, training and development programmes, and policy updates Support reporting on key people metrics (e.g. absence, turnover) Assist with HR communications and, where relevant, employee relations processes Support recruitment operations Champion the candidate experience, ensuring all recruitment queries are handled promptly and professionally Set up new roles within the ATS and build supporting automation workflows Oversee interview scheduling workflows to ensure a smooth and consistent candidate experience Step in to support recruitment operations when needed, ensuring continuity and smooth delivery Skills & Experience Experience in an HR Coordinator or HR administrative role Basic understanding of employee relations and employment law (CIPD qualification desirable) Strong organisational skills with high attention to detail Confident communicator, able to engage with stakeholders at all levels Ability to handle sensitive situations with professionalism and discretion What We Offer A collaborative and transparent company culture founded on Integrity, Innovation, and Performance. Benefits including healthcare, dental, vision, retirement planning, 30 days of holiday, and free lunches when in the office. Hybrid working pattern across our global offices in London, the US, Singapore, Zug, and Malaga. Regular Town Halls, team lunches, offsites, and social events. A strong Corporate and Social Responsibility program, including charity matching and volunteer days. Immigration and relocation support where required. Equal Opportunity Statement GSR is proudly an Equal Employment Opportunity employer. We do not discriminate based on any legally protected characteristics such as race, religion, colour, national origin, sexual orientation, gender, gender identity, gender expression, or age. We operate as a meritocracy, all aspects of hiring, promotion, and performance management are based on business needs and individual merit and competence.
About Us GSR is crypto's capital markets partner, helping founders and institutions scale with confidence. With over a decade of specialized expertise, we deliver institutional-grade market making, OTC trading, and strategic venture capital to support growth at every stage. Our value goes beyond execution. We provide access to liquidity, real-time market intelligence, and strategic guidance shaped by years operating at the center of global crypto markets. We bridge the gap between traditional finance and digital assets, connecting teams with the capital, market access, and insights they need to build what's next. The Role This role sits at the heart of the employee experience at GSR, supporting the smooth running of HR operations and helping employees navigate key moments in their journey,from joining the business through to development and beyond. You'll work closely with both employees and managers, gaining exposure across a wide range of HR activities while building a strong foundation in how a high-performing, global organisation operates. Key Responsibilities Support the employee experience end-to-end Act as a first point of contact for all general HR queries, helping employees receive clear and timely support Manage all onboarding, offboarding, and background screening processes Play a key role in creating a smooth and positive experience for new joiners Keep HR operations running smoothly Maintain accurate employee data and HR systems including payroll-related updates and coordination Support key processes such as probation reviews and performance cycles Assist managers with day-to-day HR processes and questions Contribute to broader HR work Get involved in projects such as engagement surveys, training and development programmes, and policy updates Support reporting on key people metrics (e.g. absence, turnover) Assist with HR communications and, where relevant, employee relations processes Support recruitment operations Champion the candidate experience, ensuring all recruitment queries are handled promptly and professionally Set up new roles within the ATS and build supporting automation workflows Oversee interview scheduling workflows to ensure a smooth and consistent candidate experience Step in to support recruitment operations when needed, ensuring continuity and smooth delivery Skills & Experience Experience in an HR Coordinator or HR administrative role Basic understanding of employee relations and employment law (CIPD qualification desirable) Strong organisational skills with high attention to detail Confident communicator, able to engage with stakeholders at all levels Ability to handle sensitive situations with professionalism and discretion What We Offer A collaborative and transparent company culture founded on Integrity, Innovation, and Performance. Benefits including healthcare, dental, vision, retirement planning, 30 days of holiday, and free lunches when in the office. Hybrid working pattern across our global offices in London, the US, Singapore, Zug, and Malaga. Regular Town Halls, team lunches, offsites, and social events. A strong Corporate and Social Responsibility program, including charity matching and volunteer days. Immigration and relocation support where required. Equal Opportunity Statement GSR is proudly an Equal Employment Opportunity employer. We do not discriminate based on any legally protected characteristics such as race, religion, colour, national origin, sexual orientation, gender, gender identity, gender expression, or age. We operate as a meritocracy, all aspects of hiring, promotion, and performance management are based on business needs and individual merit and competence.
SRG
Maidenhead, Berkshire
Job Title: Regulatory Affairs Manager Location: Maidenhead Contract: 12 Months / Hybrid 3 days per week onsite Hours: 37.5 hours per week Rates: 80-90p/h Job Description SRG are seeking a regulatory affairs manager for a leading pharmaceutical company based in Maidenhead. For this role you will be working in collaboration with line manager and/or Area Product Lead, is responsible for implementation of registration strategy to ensure the regulatory approval of commercially successful pharma products in the Europe region. Is responsible for ensuring effective product maintenance and lifecycle management, in line with legal/regulatory requirements and regional business needs. May also support European regulatory strategy for assets in development. Duties and Responsibilities In consultation with line manager and/or Area Product Lead; Provides clear and constructive Europe Region (Area) regulatory input and intelligence to Area and Global Regulatory & Development Project Teams via the Area and/or Global Regulatory Lead (GRL) in accordance with Area & Commercial objectives. Ensure planned drug development activities comply with Area guidelines and if they do not provide a critical analysis of the risks and issues with a remediation proposal. Support global product development strategy(s); outlining options for Scientific Advice/PIP/IMPD, coordinating preparation of briefing packages and co-ordinating and leading agency meeting preparation. Prepare strategy recommendations to global regulatory and development teams in order to shape the global product strategy in line with Area regulatory and commercial objectives Define & implement Area filing strategy (including CP, MRP, DCP); identifying risks and proposing mitigation. Lead, plan, conduct and implement regulatory activities in support of lifecycle maintenance in Area. Identify compliance risks and remediation activities proactively. GRPT & ARPT representative ensuring regulatory requirements/interests of Area & Affiliate are represented at GRPT Supports co-ordination of the review of CMC, QRD, PSUR and labelling submissions and approval of product-related packaging as required to ensure regulatory compliance. Interface with EMA or Area Health Authority(s) for products within the Therapeutic Area on behalf of the Product Lead when required. Responsible for ensuring effective planning and tracking of activities, especially submissions and key correspondence. Ensures effective planning and tracking of activities via internal tools Supports co-ordination of the review of CMC, QRD, PSUR and labelling submissions and approval of product-related packaging as required to ensure regulatory compliance. People Establishes strong and effective relationships with affiliates, area and global regulatory teams as well as cross-functional teams thereby ensuring RA activities are in line with regional business priorities. Potential to mentor less experienced Area regulatory colleagues as required Processes Follows Global Regulatory policies and procedures. Ensures that new processes are developed and implemented in order to leverage the global infrastructure and maximise efficiency, ensures that new processes are aligned with global policies, but also meet regional regulations and needs. Responsible for the Notification of Regulatory activities and RIM system entry/data accuracy for allocated projects. Responsible for ensuring forecasts are developed and actuals managed in line with regional requirements and communicating these to Area TA Head, GRL and R&D finance for assigned projects. Experience and Qualifications Graduate in Life Sciences in a relevant area. Sound knowledge of both pharmaceutical regulations and guidelines and national regulations within Area. Pharmaceutical industry experience in European Regulatory strategy development and regulatory procedures, EU centralised procedure essential. Experience of EU strategy for development assets e.g. scientific advice, paediatric investigation plans preferred. Experience working effectively across cultures and in complex matrixed environment. Excellent organizational skills and solution driven leadership style Essential Skills and Abilities Ability to prioritise and manage workload including managing multiple projects. Ability to work effectively and collaboratively across the organisation. Experienced in working effectively across cultures and in complex matrix environment. Good interpersonal and negotiation skills and the ability to influence others. Carbon60, Lorien & SRG - The Impellam Group STEM Portfolio are acting as an Employment Business in relation to this vacancy.
Job Title: Regulatory Affairs Manager Location: Maidenhead Contract: 12 Months / Hybrid 3 days per week onsite Hours: 37.5 hours per week Rates: 80-90p/h Job Description SRG are seeking a regulatory affairs manager for a leading pharmaceutical company based in Maidenhead. For this role you will be working in collaboration with line manager and/or Area Product Lead, is responsible for implementation of registration strategy to ensure the regulatory approval of commercially successful pharma products in the Europe region. Is responsible for ensuring effective product maintenance and lifecycle management, in line with legal/regulatory requirements and regional business needs. May also support European regulatory strategy for assets in development. Duties and Responsibilities In consultation with line manager and/or Area Product Lead; Provides clear and constructive Europe Region (Area) regulatory input and intelligence to Area and Global Regulatory & Development Project Teams via the Area and/or Global Regulatory Lead (GRL) in accordance with Area & Commercial objectives. Ensure planned drug development activities comply with Area guidelines and if they do not provide a critical analysis of the risks and issues with a remediation proposal. Support global product development strategy(s); outlining options for Scientific Advice/PIP/IMPD, coordinating preparation of briefing packages and co-ordinating and leading agency meeting preparation. Prepare strategy recommendations to global regulatory and development teams in order to shape the global product strategy in line with Area regulatory and commercial objectives Define & implement Area filing strategy (including CP, MRP, DCP); identifying risks and proposing mitigation. Lead, plan, conduct and implement regulatory activities in support of lifecycle maintenance in Area. Identify compliance risks and remediation activities proactively. GRPT & ARPT representative ensuring regulatory requirements/interests of Area & Affiliate are represented at GRPT Supports co-ordination of the review of CMC, QRD, PSUR and labelling submissions and approval of product-related packaging as required to ensure regulatory compliance. Interface with EMA or Area Health Authority(s) for products within the Therapeutic Area on behalf of the Product Lead when required. Responsible for ensuring effective planning and tracking of activities, especially submissions and key correspondence. Ensures effective planning and tracking of activities via internal tools Supports co-ordination of the review of CMC, QRD, PSUR and labelling submissions and approval of product-related packaging as required to ensure regulatory compliance. People Establishes strong and effective relationships with affiliates, area and global regulatory teams as well as cross-functional teams thereby ensuring RA activities are in line with regional business priorities. Potential to mentor less experienced Area regulatory colleagues as required Processes Follows Global Regulatory policies and procedures. Ensures that new processes are developed and implemented in order to leverage the global infrastructure and maximise efficiency, ensures that new processes are aligned with global policies, but also meet regional regulations and needs. Responsible for the Notification of Regulatory activities and RIM system entry/data accuracy for allocated projects. Responsible for ensuring forecasts are developed and actuals managed in line with regional requirements and communicating these to Area TA Head, GRL and R&D finance for assigned projects. Experience and Qualifications Graduate in Life Sciences in a relevant area. Sound knowledge of both pharmaceutical regulations and guidelines and national regulations within Area. Pharmaceutical industry experience in European Regulatory strategy development and regulatory procedures, EU centralised procedure essential. Experience of EU strategy for development assets e.g. scientific advice, paediatric investigation plans preferred. Experience working effectively across cultures and in complex matrixed environment. Excellent organizational skills and solution driven leadership style Essential Skills and Abilities Ability to prioritise and manage workload including managing multiple projects. Ability to work effectively and collaboratively across the organisation. Experienced in working effectively across cultures and in complex matrix environment. Good interpersonal and negotiation skills and the ability to influence others. Carbon60, Lorien & SRG - The Impellam Group STEM Portfolio are acting as an Employment Business in relation to this vacancy.
IQVIA
Reading, Berkshire
The Senior Clinical Trial Manager will be responsible for managing clinical trial sites from study startup throughout the course of the clinical trials until site close out. They will work to oversee that all aspects of the conduct of the trial sites and or across their assigned assets are in compliance with the study protocol, study operation plans, ICH current GCPs, and regulatory requirements. They will work collaboratively with the Sponsor Clinical Project Manager (CPM), Clinical Research Organization (CRO) representative(s), vendors and other Sponsor functional departments (as required) to drive start-up and ongoing oversight of clinical studies. They may have direct reports of Clinical Trial Managers across the clinical operations portfolios ensuring their clinical program deliverables are delivered to time, cost and quality. Responsabilities: Participate in the planning, implementation and management of sponsor clinical trials/assets in compliance with industry regulations, ICH-GCP and applicable sponsor controlled documents. Oversee the site management of CROs and clinical trial sites to ensure delivery, per scope of work or contractual agreements, meet recruitment targets and deliver high quality data on time. Track site visit and trip report metrics; data quality concerns and site level trending of protocol deviations. Conduct oversight site visits including pharmacy visits, as required, to evaluate site and CRA performance and ensure adherence to study protocols, study operation plans, ICH GCP and regulatory requirements Attend and assist, as required, at Initiation visits to confirm site training of therapeutic indication(s) and associated study procedures (e.g. Pharmacy training) and help build and foster sponsor-CRO-Investigator - site relationships Review a percentage of CRA monitoring trip reports, ensuring oversight of CRO CRA and Site compliance with protocol, study plans, SOPs and ICH and GCPs, escalate identified report issues and ensure CRO study team resolve identified concerns • Collaborate with sponsor CPM and sponsor Medical Monitor for country and site identification, feasibility and selection to optimize processes to ensure efficient start-up timelines are met. Manage study start up in collaboration with internal and external project teams (e.g. sponsor Project Manager, Regulatory, Clinical Supplies, Third Party Vendors, CRO) to ensure start up timelines are clearly defined and implemented, working to identify any risks and resolving any issues. Act as subject matter expert for assigned protocols for study related issues, protocol and clinical operational queries arising from CRO, IRB/IECs/RAs, Third Party Vendors and sites. Provide routine updates to the internal project team on study status/issues Manages the CRO/clinical trial site during start-up activities including, but not limited to, budget and contract negotiations, IRB/EC submissions and response and facilitation of essential document collection Provide direction and support to the CPM in ensuring consistency of Clinical Operations processes across clinical trials and regions, identifying areas where trial specific or regional differences are appropriate. Manages consistency of Clinical Operations processes across clinical trials and regions, identifying areas where trial specific or regional differences are appropriate Works cross-functionally with other sponsor departments (Clinical Supplies, Quality Assurance, Regulatory Affairs) to ensure all clinical trial activities performed by sponsor as a Sponsor are performed according to study requirements and timelines. Contribute to the development and/or participate in the review of study related documents including (but not limited to) site feasibility, protocol, informed consent documents (master and/or site specific), budgets, monitoring plans, regulatory and start-up plans, patient recruitment plans, pharmacy and lab manuals, case report form development and training materials Execute and/or deliver trial specific training as required Review of open action items and data trends; working with CROs to escalate and resolve identified issues to ensure standards for monitoring and reporting are met as well as to ensure better efficiencies and execution of our studies Contribute to the development of and oversees implementation of patient recruitment and retention strategies and acts on any deviations from plan Support study team with site selection while optimizing start-up processes to ensure efficient start-up timelines are met. Attend and present at Investigator Meetings on Clinical Operations topics, as required May oversee the accurate, timely, and complete tracking of laboratory samples May represent Clinical Operations in cross-functional initiatives (e.g., start-up, continued process improvements with CROs). Contribute to the development and/or participate in the review of sponsor SOPs, Work Instructions and team policies Contribute to preparation of investigator newsletters or email newsflashes. Supports the internal and external project teams with audits/inspection readiness and activities, resolution of audit/inspection findings and contribution to CAPAs as required Oversight of direct report(s) study execution and procedures as required to ensure regulatory compliance of protocol activities, if appropriate Accountable for ensuring all study deliverables and milestones are met with quality and within timelines Provide direction and support to direct report(s) to ensure consistent approach and process to study execution and procedures amongst various program assets Provides support/escalation point for direct reports as needed Profile: At least 8 years of relevant clinical operational experience in a biotechnology/pharmaceutical company, and/or CRO Working knowledge of GCP, ICH, GDP and relevant CFRs is required; familiarity with MHRA/EMA/CHMP regulations and guidelines and other international regulatory requirements is a plus Experience with start-up and initiation of clinical trial sites Experience creating and maintaining healthy and creative relationships with clinical trial sites and Principal Investigators, helping to support and influence where required Ability to communicate and coordinate activities with the internal team, clinical sites and vendors Proactively identify project challenges/risks and appropriate corrective actions to the internal study teams and work with internal team, clinical sites and vendors on resolutions with minimal supervision Ability to work independently Experience presenting high level presentations, both orally and in writing Knowledge of and experience with immunotherapies and/or Oncology At least 2 years of on-site monitoring experience IQVIA is a leading global provider of clinical research services, commercial insights and healthcare intelligence to the life sciences and healthcare industries. We create intelligent connections to accelerate the development and commercialization of innovative medical treatments to help improve patient outcomes and population health worldwide . Learn more at
The Senior Clinical Trial Manager will be responsible for managing clinical trial sites from study startup throughout the course of the clinical trials until site close out. They will work to oversee that all aspects of the conduct of the trial sites and or across their assigned assets are in compliance with the study protocol, study operation plans, ICH current GCPs, and regulatory requirements. They will work collaboratively with the Sponsor Clinical Project Manager (CPM), Clinical Research Organization (CRO) representative(s), vendors and other Sponsor functional departments (as required) to drive start-up and ongoing oversight of clinical studies. They may have direct reports of Clinical Trial Managers across the clinical operations portfolios ensuring their clinical program deliverables are delivered to time, cost and quality. Responsabilities: Participate in the planning, implementation and management of sponsor clinical trials/assets in compliance with industry regulations, ICH-GCP and applicable sponsor controlled documents. Oversee the site management of CROs and clinical trial sites to ensure delivery, per scope of work or contractual agreements, meet recruitment targets and deliver high quality data on time. Track site visit and trip report metrics; data quality concerns and site level trending of protocol deviations. Conduct oversight site visits including pharmacy visits, as required, to evaluate site and CRA performance and ensure adherence to study protocols, study operation plans, ICH GCP and regulatory requirements Attend and assist, as required, at Initiation visits to confirm site training of therapeutic indication(s) and associated study procedures (e.g. Pharmacy training) and help build and foster sponsor-CRO-Investigator - site relationships Review a percentage of CRA monitoring trip reports, ensuring oversight of CRO CRA and Site compliance with protocol, study plans, SOPs and ICH and GCPs, escalate identified report issues and ensure CRO study team resolve identified concerns • Collaborate with sponsor CPM and sponsor Medical Monitor for country and site identification, feasibility and selection to optimize processes to ensure efficient start-up timelines are met. Manage study start up in collaboration with internal and external project teams (e.g. sponsor Project Manager, Regulatory, Clinical Supplies, Third Party Vendors, CRO) to ensure start up timelines are clearly defined and implemented, working to identify any risks and resolving any issues. Act as subject matter expert for assigned protocols for study related issues, protocol and clinical operational queries arising from CRO, IRB/IECs/RAs, Third Party Vendors and sites. Provide routine updates to the internal project team on study status/issues Manages the CRO/clinical trial site during start-up activities including, but not limited to, budget and contract negotiations, IRB/EC submissions and response and facilitation of essential document collection Provide direction and support to the CPM in ensuring consistency of Clinical Operations processes across clinical trials and regions, identifying areas where trial specific or regional differences are appropriate. Manages consistency of Clinical Operations processes across clinical trials and regions, identifying areas where trial specific or regional differences are appropriate Works cross-functionally with other sponsor departments (Clinical Supplies, Quality Assurance, Regulatory Affairs) to ensure all clinical trial activities performed by sponsor as a Sponsor are performed according to study requirements and timelines. Contribute to the development and/or participate in the review of study related documents including (but not limited to) site feasibility, protocol, informed consent documents (master and/or site specific), budgets, monitoring plans, regulatory and start-up plans, patient recruitment plans, pharmacy and lab manuals, case report form development and training materials Execute and/or deliver trial specific training as required Review of open action items and data trends; working with CROs to escalate and resolve identified issues to ensure standards for monitoring and reporting are met as well as to ensure better efficiencies and execution of our studies Contribute to the development of and oversees implementation of patient recruitment and retention strategies and acts on any deviations from plan Support study team with site selection while optimizing start-up processes to ensure efficient start-up timelines are met. Attend and present at Investigator Meetings on Clinical Operations topics, as required May oversee the accurate, timely, and complete tracking of laboratory samples May represent Clinical Operations in cross-functional initiatives (e.g., start-up, continued process improvements with CROs). Contribute to the development and/or participate in the review of sponsor SOPs, Work Instructions and team policies Contribute to preparation of investigator newsletters or email newsflashes. Supports the internal and external project teams with audits/inspection readiness and activities, resolution of audit/inspection findings and contribution to CAPAs as required Oversight of direct report(s) study execution and procedures as required to ensure regulatory compliance of protocol activities, if appropriate Accountable for ensuring all study deliverables and milestones are met with quality and within timelines Provide direction and support to direct report(s) to ensure consistent approach and process to study execution and procedures amongst various program assets Provides support/escalation point for direct reports as needed Profile: At least 8 years of relevant clinical operational experience in a biotechnology/pharmaceutical company, and/or CRO Working knowledge of GCP, ICH, GDP and relevant CFRs is required; familiarity with MHRA/EMA/CHMP regulations and guidelines and other international regulatory requirements is a plus Experience with start-up and initiation of clinical trial sites Experience creating and maintaining healthy and creative relationships with clinical trial sites and Principal Investigators, helping to support and influence where required Ability to communicate and coordinate activities with the internal team, clinical sites and vendors Proactively identify project challenges/risks and appropriate corrective actions to the internal study teams and work with internal team, clinical sites and vendors on resolutions with minimal supervision Ability to work independently Experience presenting high level presentations, both orally and in writing Knowledge of and experience with immunotherapies and/or Oncology At least 2 years of on-site monitoring experience IQVIA is a leading global provider of clinical research services, commercial insights and healthcare intelligence to the life sciences and healthcare industries. We create intelligent connections to accelerate the development and commercialization of innovative medical treatments to help improve patient outcomes and population health worldwide . Learn more at
