If you are a current Jazz employee please apply via the Internal Career site. Jazz Pharmaceuticals is a global biopharma company whose purpose is to innovate to transform the lives of patients and their families. We are dedicated to developing life-changing medicines for people with serious diseases - often with limited or no therapeutic options. We have a diverse portfolio of marketed medicines, including leading therapies for sleep disorders and epilepsy, and a growing portfolio of cancer treatments. Our patient-focused and science-driven approach powers pioneering research and development advancements across our robust pipeline of innovative therapeutics in oncology and neuroscience. Jazz is headquartered in Dublin, Ireland with research and development laboratories, manufacturing facilities and employees in multiple countries committed to serving patients worldwide. Please visit for more information. Brief Description: A key contributor within the Team, having the following responsibility and accountability. Responsible for planning, execution and reporting of all aspects of project related work. Hands on approach to all aspects of work to ensure mentorship and team strength is achieved. Achievement of all departmental and project related goals in a timely manner. Accountable for applying appropriate scientific rigor, building in quality and managing risk to ensure good quality, scientific outcomes. Demonstration of collaborative and positive behaviors. An appropriate level of knowledge and experience will be required to mentor junior team members and provide key scientific expertise as input to various projects within the department in support of functional matrix teams for robust, phase appropriate development of oral liquid and solid dosage drug products. Essential Functions/Responsibilities Maintain and provide in-depth knowledge and expertise on the drug development process and relevant new technologies. Practical and theoretical understanding in a range of scientific skills and technologies associated with drug substance and drug product development/ manufacture at all lifecycle stages. Demonstrate competency and innovation on a range of complex skills and instruments, associated with the characterisation of oral liquid and solid dosage forms. Contribute toward process driven continuous improvement initiatives with consideration for the team, the department, and the company. Record and review all experimental outcomes in an appropriate format and support junior scientists to ensure the same high standards are maintained across the team. Lead and mentor in the design of protocols and experimental work Report and communicate project outcomes in an appropriate manner. Identify and resolve promptly any problems occurring at any phase of a study, escalating to the line manager where necessary. Maintain all areas of the laboratory in a safe, clean and tidy state. Maintain a safety first approach and ensure that cGxP is followed at all times. Ensure training record is maintained to cGxP. Ensure all applicable quality measures are met and adhered to. Assist in the creation and maintenance of all relevant cGxP documents. The role holder is responsible for maintaining cGxP and Health and Safety Knowledge relevant to the role. Write or constructively review S.O.P's, Protocols, technical reports, risk assessments as required. Required Knowledge, Skills, and Abilities Relevant working knowledge of material science principles applied to pharmaceutical development, including excipient functionality, solid-state characterization, and stability. Experience with material characterization techniques such as DSC, TGA, XRPD, SEM, Microscopy, particle size analysis, and rheology. Understanding of material properties and their impact on drug product performance, manufacturability, and lifecycle development. Knowledge of regulatory expectations related to material science in pharmaceutical development (e.g., ICH guidelines, compendial standards). Demonstrated experience in supporting drug substance, formulation and process development through material science insights. Ability to troubleshoot technical issues related to material attributes and propose science-based solutions. Proven communication skills, including technical writing, presentation of complex data, and cross-functional collaboration. Authorship of technical documentation, including material risk assessments, characterization reports, and regulatory submission content. Ability to coach and mentor junior scientists and contribute to capability building within the team. Required/Preferred Education and Licenses Degree plus appropriate industry experience or PhD in a relevant field with appropriate industry experience. Awareness of risk management principles desirable. Awareness of project management principles desirable. Jazz Pharmaceuticals is an equal opportunity/affirmative action employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, or any characteristic protected by law. The successful candidate will also be eligible to participate in various benefits offerings, including, but not limited to, medical, dental and vision insurance, retirement savings plan, and flexible paid vacation. For more information on our Benefits offerings please click here: .
Oct 08, 2025
Full time
If you are a current Jazz employee please apply via the Internal Career site. Jazz Pharmaceuticals is a global biopharma company whose purpose is to innovate to transform the lives of patients and their families. We are dedicated to developing life-changing medicines for people with serious diseases - often with limited or no therapeutic options. We have a diverse portfolio of marketed medicines, including leading therapies for sleep disorders and epilepsy, and a growing portfolio of cancer treatments. Our patient-focused and science-driven approach powers pioneering research and development advancements across our robust pipeline of innovative therapeutics in oncology and neuroscience. Jazz is headquartered in Dublin, Ireland with research and development laboratories, manufacturing facilities and employees in multiple countries committed to serving patients worldwide. Please visit for more information. Brief Description: A key contributor within the Team, having the following responsibility and accountability. Responsible for planning, execution and reporting of all aspects of project related work. Hands on approach to all aspects of work to ensure mentorship and team strength is achieved. Achievement of all departmental and project related goals in a timely manner. Accountable for applying appropriate scientific rigor, building in quality and managing risk to ensure good quality, scientific outcomes. Demonstration of collaborative and positive behaviors. An appropriate level of knowledge and experience will be required to mentor junior team members and provide key scientific expertise as input to various projects within the department in support of functional matrix teams for robust, phase appropriate development of oral liquid and solid dosage drug products. Essential Functions/Responsibilities Maintain and provide in-depth knowledge and expertise on the drug development process and relevant new technologies. Practical and theoretical understanding in a range of scientific skills and technologies associated with drug substance and drug product development/ manufacture at all lifecycle stages. Demonstrate competency and innovation on a range of complex skills and instruments, associated with the characterisation of oral liquid and solid dosage forms. Contribute toward process driven continuous improvement initiatives with consideration for the team, the department, and the company. Record and review all experimental outcomes in an appropriate format and support junior scientists to ensure the same high standards are maintained across the team. Lead and mentor in the design of protocols and experimental work Report and communicate project outcomes in an appropriate manner. Identify and resolve promptly any problems occurring at any phase of a study, escalating to the line manager where necessary. Maintain all areas of the laboratory in a safe, clean and tidy state. Maintain a safety first approach and ensure that cGxP is followed at all times. Ensure training record is maintained to cGxP. Ensure all applicable quality measures are met and adhered to. Assist in the creation and maintenance of all relevant cGxP documents. The role holder is responsible for maintaining cGxP and Health and Safety Knowledge relevant to the role. Write or constructively review S.O.P's, Protocols, technical reports, risk assessments as required. Required Knowledge, Skills, and Abilities Relevant working knowledge of material science principles applied to pharmaceutical development, including excipient functionality, solid-state characterization, and stability. Experience with material characterization techniques such as DSC, TGA, XRPD, SEM, Microscopy, particle size analysis, and rheology. Understanding of material properties and their impact on drug product performance, manufacturability, and lifecycle development. Knowledge of regulatory expectations related to material science in pharmaceutical development (e.g., ICH guidelines, compendial standards). Demonstrated experience in supporting drug substance, formulation and process development through material science insights. Ability to troubleshoot technical issues related to material attributes and propose science-based solutions. Proven communication skills, including technical writing, presentation of complex data, and cross-functional collaboration. Authorship of technical documentation, including material risk assessments, characterization reports, and regulatory submission content. Ability to coach and mentor junior scientists and contribute to capability building within the team. Required/Preferred Education and Licenses Degree plus appropriate industry experience or PhD in a relevant field with appropriate industry experience. Awareness of risk management principles desirable. Awareness of project management principles desirable. Jazz Pharmaceuticals is an equal opportunity/affirmative action employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, or any characteristic protected by law. The successful candidate will also be eligible to participate in various benefits offerings, including, but not limited to, medical, dental and vision insurance, retirement savings plan, and flexible paid vacation. For more information on our Benefits offerings please click here: .
If you are a current Jazz employee please apply via the Internal Career site. Jazz Pharmaceuticals is a global biopharma company whose purpose is to innovate to transform the lives of patients and their families. We are dedicated to developing life-changing medicines for people with serious diseases - often with limited or no therapeutic options. We have a diverse portfolio of marketed medicines, including leading therapies for sleep disorders and epilepsy, and a growing portfolio of cancer treatments. Our patient-focused and science-driven approach powers pioneering research and development advancements across our robust pipeline of innovative therapeutics in oncology and neuroscience. Jazz is headquartered in Dublin, Ireland with research and development laboratories, manufacturing facilities and employees in multiple countries committed to serving patients worldwide. Please visit for more information. Brief Description: A key contributor within the Team, having the following responsibility and accountability. Responsible for planning, execution and reporting of all aspects of project related work. Hands on approach to all aspects of work to ensure mentorship and team strength is achieved. Achievement of all departmental and project related goals in a timely manner. Accountable for applying appropriate scientific rigor, building in quality and managing risk to ensure good quality, scientific outcomes. Demonstration of collaborative and positive behaviors. An appropriate level of knowledge and experience will be required to mentor junior team members and provide key scientific expertise as input to various projects within the department in support of functional matrix teams for robust, phase appropriate development of oral liquid and solid dosage drug products. Essential Functions/Responsibilities Maintain and provide in-depth knowledge and expertise on the drug development process and relevant new technologies. Practical and theoretical understanding in a range of scientific skills and technologies associated with drug substance and drug product development/ manufacture at all lifecycle stages. Demonstrate competency and innovation on a range of complex skills and instruments, associated with the characterisation of oral liquid and solid dosage forms. Contribute toward process driven continuous improvement initiatives with consideration for the team, the department, and the company. Record and review all experimental outcomes in an appropriate format and support junior scientists to ensure the same high standards are maintained across the team. Lead and mentor in the design of protocols and experimental work Report and communicate project outcomes in an appropriate manner. Identify and resolve promptly any problems occurring at any phase of a study, escalating to the line manager where necessary. Maintain all areas of the laboratory in a safe, clean and tidy state. Maintain a safety first approach and ensure that cGxP is followed at all times. Ensure training record is maintained to cGxP. Ensure all applicable quality measures are met and adhered to. Assist in the creation and maintenance of all relevant cGxP documents. The role holder is responsible for maintaining cGxP and Health and Safety Knowledge relevant to the role. Write or constructively review S.O.P's, Protocols, technical reports, risk assessments as required. Required Knowledge, Skills, and Abilities Relevant working knowledge of material science principles applied to pharmaceutical development, including excipient functionality, solid-state characterization, and stability. Experience with material characterization techniques such as DSC, TGA, XRPD, SEM, Microscopy, particle size analysis, and rheology. Understanding of material properties and their impact on drug product performance, manufacturability, and lifecycle development. Knowledge of regulatory expectations related to material science in pharmaceutical development (e.g., ICH guidelines, compendial standards). Demonstrated experience in supporting drug substance, formulation and process development through material science insights. Ability to troubleshoot technical issues related to material attributes and propose science-based solutions. Proven communication skills, including technical writing, presentation of complex data, and cross-functional collaboration. Authorship of technical documentation, including material risk assessments, characterization reports, and regulatory submission content. Ability to coach and mentor junior scientists and contribute to capability building within the team. Required/Preferred Education and Licenses Degree plus appropriate industry experience or PhD in a relevant field with appropriate industry experience. Awareness of risk management principles desirable. Awareness of project management principles desirable. Jazz Pharmaceuticals is an equal opportunity/affirmative action employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, or any characteristic protected by law. The successful candidate will also be eligible to participate in various benefits offerings, including, but not limited to, medical, dental and vision insurance, retirement savings plan, and flexible paid vacation. For more information on our Benefits offerings please click here: .
Oct 07, 2025
Full time
If you are a current Jazz employee please apply via the Internal Career site. Jazz Pharmaceuticals is a global biopharma company whose purpose is to innovate to transform the lives of patients and their families. We are dedicated to developing life-changing medicines for people with serious diseases - often with limited or no therapeutic options. We have a diverse portfolio of marketed medicines, including leading therapies for sleep disorders and epilepsy, and a growing portfolio of cancer treatments. Our patient-focused and science-driven approach powers pioneering research and development advancements across our robust pipeline of innovative therapeutics in oncology and neuroscience. Jazz is headquartered in Dublin, Ireland with research and development laboratories, manufacturing facilities and employees in multiple countries committed to serving patients worldwide. Please visit for more information. Brief Description: A key contributor within the Team, having the following responsibility and accountability. Responsible for planning, execution and reporting of all aspects of project related work. Hands on approach to all aspects of work to ensure mentorship and team strength is achieved. Achievement of all departmental and project related goals in a timely manner. Accountable for applying appropriate scientific rigor, building in quality and managing risk to ensure good quality, scientific outcomes. Demonstration of collaborative and positive behaviors. An appropriate level of knowledge and experience will be required to mentor junior team members and provide key scientific expertise as input to various projects within the department in support of functional matrix teams for robust, phase appropriate development of oral liquid and solid dosage drug products. Essential Functions/Responsibilities Maintain and provide in-depth knowledge and expertise on the drug development process and relevant new technologies. Practical and theoretical understanding in a range of scientific skills and technologies associated with drug substance and drug product development/ manufacture at all lifecycle stages. Demonstrate competency and innovation on a range of complex skills and instruments, associated with the characterisation of oral liquid and solid dosage forms. Contribute toward process driven continuous improvement initiatives with consideration for the team, the department, and the company. Record and review all experimental outcomes in an appropriate format and support junior scientists to ensure the same high standards are maintained across the team. Lead and mentor in the design of protocols and experimental work Report and communicate project outcomes in an appropriate manner. Identify and resolve promptly any problems occurring at any phase of a study, escalating to the line manager where necessary. Maintain all areas of the laboratory in a safe, clean and tidy state. Maintain a safety first approach and ensure that cGxP is followed at all times. Ensure training record is maintained to cGxP. Ensure all applicable quality measures are met and adhered to. Assist in the creation and maintenance of all relevant cGxP documents. The role holder is responsible for maintaining cGxP and Health and Safety Knowledge relevant to the role. Write or constructively review S.O.P's, Protocols, technical reports, risk assessments as required. Required Knowledge, Skills, and Abilities Relevant working knowledge of material science principles applied to pharmaceutical development, including excipient functionality, solid-state characterization, and stability. Experience with material characterization techniques such as DSC, TGA, XRPD, SEM, Microscopy, particle size analysis, and rheology. Understanding of material properties and their impact on drug product performance, manufacturability, and lifecycle development. Knowledge of regulatory expectations related to material science in pharmaceutical development (e.g., ICH guidelines, compendial standards). Demonstrated experience in supporting drug substance, formulation and process development through material science insights. Ability to troubleshoot technical issues related to material attributes and propose science-based solutions. Proven communication skills, including technical writing, presentation of complex data, and cross-functional collaboration. Authorship of technical documentation, including material risk assessments, characterization reports, and regulatory submission content. Ability to coach and mentor junior scientists and contribute to capability building within the team. Required/Preferred Education and Licenses Degree plus appropriate industry experience or PhD in a relevant field with appropriate industry experience. Awareness of risk management principles desirable. Awareness of project management principles desirable. Jazz Pharmaceuticals is an equal opportunity/affirmative action employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, or any characteristic protected by law. The successful candidate will also be eligible to participate in various benefits offerings, including, but not limited to, medical, dental and vision insurance, retirement savings plan, and flexible paid vacation. For more information on our Benefits offerings please click here: .
Walker Cole International is searching for a Senior R&D Scientist - E&L and Nitrosamine Method Development - to join a global pharmaceutical company at their R&D and GMP-regulated site in the UK. As the Senior Scientist, you will play a key role in developing and validating analytical methods to support Extractables, Leachables, and Nitrosamine testing across pharmaceutical products and materials. Your responsibilities will include: Leading and supporting risk assessments and analytical method development for E&L and Nitrosamines. Developing, validating, and transferring LC-MS and GC-MS methods in compliance with GMP and regulatory guidelines. Performing data interpretation, troubleshooting, and technical investigations to resolve analytical issues. Preparing technical reports and regulatory documentation to support product filings and submissions. Collaborating with QC, QA, and Regulatory Affairs teams to ensure analytical compliance and product quality. Contributing to continuous improvement within analytical R&D and supporting method optimisation projects. To be successful, you will have: Proven experience in Extractables & Leachables and/or Nitrosamine analysis within a GMP-regulated laboratory. Hands-on experience with LC-MS or GC-MS and method validation techniques. Strong problem-solving, communication, and documentation skills. Analytical Chemistry Extractables & Leachables Nitrosamines LC-MS GC-MS Method Development Validation GMP Pharmaceuticals R&D
Oct 06, 2025
Full time
Walker Cole International is searching for a Senior R&D Scientist - E&L and Nitrosamine Method Development - to join a global pharmaceutical company at their R&D and GMP-regulated site in the UK. As the Senior Scientist, you will play a key role in developing and validating analytical methods to support Extractables, Leachables, and Nitrosamine testing across pharmaceutical products and materials. Your responsibilities will include: Leading and supporting risk assessments and analytical method development for E&L and Nitrosamines. Developing, validating, and transferring LC-MS and GC-MS methods in compliance with GMP and regulatory guidelines. Performing data interpretation, troubleshooting, and technical investigations to resolve analytical issues. Preparing technical reports and regulatory documentation to support product filings and submissions. Collaborating with QC, QA, and Regulatory Affairs teams to ensure analytical compliance and product quality. Contributing to continuous improvement within analytical R&D and supporting method optimisation projects. To be successful, you will have: Proven experience in Extractables & Leachables and/or Nitrosamine analysis within a GMP-regulated laboratory. Hands-on experience with LC-MS or GC-MS and method validation techniques. Strong problem-solving, communication, and documentation skills. Analytical Chemistry Extractables & Leachables Nitrosamines LC-MS GC-MS Method Development Validation GMP Pharmaceuticals R&D
If you are a current Jazz employee please apply via the Internal Career site. Jazz Pharmaceuticals is a global biopharma company whose purpose is to innovate to transform the lives of patients and their families. We are dedicated to developing life-changing medicines for people with serious diseases - often with limited or no therapeutic options. We have a diverse portfolio of marketed medicines, including leading therapies for sleep disorders and epilepsy, and a growing portfolio of cancer treatments. Our patient-focused and science-driven approach powers pioneering research and development advancements across our robust pipeline of innovative therapeutics in oncology and neuroscience. Jazz is headquartered in Dublin, Ireland with research and development laboratories, manufacturing facilities and employees in multiple countries committed to serving patients worldwide. Please visit for more information. Brief Description: A key contributor within the Team, having the following responsibility and accountability. Responsible for planning, execution and reporting of all aspects of project related work. Hands on approach to all aspects of work to ensure mentorship and team strength is achieved. Achievement of all departmental and project related goals in a timely manner. Accountable for applying appropriate scientific rigor, building in quality and managing risk to ensure good quality, scientific outcomes. Demonstration of collaborative and positive behaviors. An appropriate level of knowledge and experience will be required to mentor junior team members and provide key scientific expertise as input to various projects within the department in support of functional matrix teams for robust, phase appropriate development of oral liquid and solid dosage drug products. Essential Functions/Responsibilities Maintain and provide in-depth knowledge and expertise on the drug development process and relevant new technologies. Practical and theoretical understanding in a range of scientific skills and technologies associated with drug substance and drug product development/ manufacture at all lifecycle stages. Demonstrate competency and innovation on a range of complex skills and instruments, associated with the characterisation of oral liquid and solid dosage forms. Contribute toward process driven continuous improvement initiatives with consideration for the team, the department, and the company. Record and review all experimental outcomes in an appropriate format and support junior scientists to ensure the same high standards are maintained across the team. Lead and mentor in the design of protocols and experimental work Report and communicate project outcomes in an appropriate manner. Identify and resolve promptly any problems occurring at any phase of a study, escalating to the line manager where necessary. Maintain all areas of the laboratory in a safe, clean and tidy state. Maintain a safety first approach and ensure that cGxP is followed at all times. Ensure training record is maintained to cGxP. Ensure all applicable quality measures are met and adhered to. Assist in the creation and maintenance of all relevant cGxP documents. The role holder is responsible for maintaining cGxP and Health and Safety Knowledge relevant to the role. Write or constructively review S.O.P's, Protocols, technical reports, risk assessments as required. Required Knowledge, Skills, and Abilities Relevant working knowledge of material science principles applied to pharmaceutical development, including excipient functionality, solid-state characterization, and stability. Experience with material characterization techniques such as DSC, TGA, XRPD, SEM, Microscopy, particle size analysis, and rheology. Understanding of material properties and their impact on drug product performance, manufacturability, and lifecycle development. Knowledge of regulatory expectations related to material science in pharmaceutical development (e.g., ICH guidelines, compendial standards). Demonstrated experience in supporting drug substance, formulation and process development through material science insights. Ability to troubleshoot technical issues related to material attributes and propose science-based solutions. Proven communication skills, including technical writing, presentation of complex data, and cross-functional collaboration. Authorship of technical documentation, including material risk assessments, characterization reports, and regulatory submission content. Ability to coach and mentor junior scientists and contribute to capability building within the team. Required/Preferred Education and Licenses Degree plus appropriate industry experience or PhD in a relevant field with appropriate industry experience. Awareness of risk management principles desirable. Awareness of project management principles desirable. Jazz Pharmaceuticals is an equal opportunity/affirmative action employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, or any characteristic protected by law. The successful candidate will also be eligible to participate in various benefits offerings, including, but not limited to, medical, dental and vision insurance, retirement savings plan, and flexible paid vacation. For more information on our Benefits offerings please click here: .
Oct 04, 2025
Full time
If you are a current Jazz employee please apply via the Internal Career site. Jazz Pharmaceuticals is a global biopharma company whose purpose is to innovate to transform the lives of patients and their families. We are dedicated to developing life-changing medicines for people with serious diseases - often with limited or no therapeutic options. We have a diverse portfolio of marketed medicines, including leading therapies for sleep disorders and epilepsy, and a growing portfolio of cancer treatments. Our patient-focused and science-driven approach powers pioneering research and development advancements across our robust pipeline of innovative therapeutics in oncology and neuroscience. Jazz is headquartered in Dublin, Ireland with research and development laboratories, manufacturing facilities and employees in multiple countries committed to serving patients worldwide. Please visit for more information. Brief Description: A key contributor within the Team, having the following responsibility and accountability. Responsible for planning, execution and reporting of all aspects of project related work. Hands on approach to all aspects of work to ensure mentorship and team strength is achieved. Achievement of all departmental and project related goals in a timely manner. Accountable for applying appropriate scientific rigor, building in quality and managing risk to ensure good quality, scientific outcomes. Demonstration of collaborative and positive behaviors. An appropriate level of knowledge and experience will be required to mentor junior team members and provide key scientific expertise as input to various projects within the department in support of functional matrix teams for robust, phase appropriate development of oral liquid and solid dosage drug products. Essential Functions/Responsibilities Maintain and provide in-depth knowledge and expertise on the drug development process and relevant new technologies. Practical and theoretical understanding in a range of scientific skills and technologies associated with drug substance and drug product development/ manufacture at all lifecycle stages. Demonstrate competency and innovation on a range of complex skills and instruments, associated with the characterisation of oral liquid and solid dosage forms. Contribute toward process driven continuous improvement initiatives with consideration for the team, the department, and the company. Record and review all experimental outcomes in an appropriate format and support junior scientists to ensure the same high standards are maintained across the team. Lead and mentor in the design of protocols and experimental work Report and communicate project outcomes in an appropriate manner. Identify and resolve promptly any problems occurring at any phase of a study, escalating to the line manager where necessary. Maintain all areas of the laboratory in a safe, clean and tidy state. Maintain a safety first approach and ensure that cGxP is followed at all times. Ensure training record is maintained to cGxP. Ensure all applicable quality measures are met and adhered to. Assist in the creation and maintenance of all relevant cGxP documents. The role holder is responsible for maintaining cGxP and Health and Safety Knowledge relevant to the role. Write or constructively review S.O.P's, Protocols, technical reports, risk assessments as required. Required Knowledge, Skills, and Abilities Relevant working knowledge of material science principles applied to pharmaceutical development, including excipient functionality, solid-state characterization, and stability. Experience with material characterization techniques such as DSC, TGA, XRPD, SEM, Microscopy, particle size analysis, and rheology. Understanding of material properties and their impact on drug product performance, manufacturability, and lifecycle development. Knowledge of regulatory expectations related to material science in pharmaceutical development (e.g., ICH guidelines, compendial standards). Demonstrated experience in supporting drug substance, formulation and process development through material science insights. Ability to troubleshoot technical issues related to material attributes and propose science-based solutions. Proven communication skills, including technical writing, presentation of complex data, and cross-functional collaboration. Authorship of technical documentation, including material risk assessments, characterization reports, and regulatory submission content. Ability to coach and mentor junior scientists and contribute to capability building within the team. Required/Preferred Education and Licenses Degree plus appropriate industry experience or PhD in a relevant field with appropriate industry experience. Awareness of risk management principles desirable. Awareness of project management principles desirable. Jazz Pharmaceuticals is an equal opportunity/affirmative action employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, or any characteristic protected by law. The successful candidate will also be eligible to participate in various benefits offerings, including, but not limited to, medical, dental and vision insurance, retirement savings plan, and flexible paid vacation. For more information on our Benefits offerings please click here: .
If you are a current Jazz employee please apply via the Internal Career site. Jazz Pharmaceuticals is a global biopharma company whose purpose is to innovate to transform the lives of patients and their families. We are dedicated to developing life-changing medicines for people with serious diseases - often with limited or no therapeutic options. We have a diverse portfolio of marketed medicines, including leading therapies for sleep disorders and epilepsy, and a growing portfolio of cancer treatments. Our patient-focused and science-driven approach powers pioneering research and development advancements across our robust pipeline of innovative therapeutics in oncology and neuroscience. Jazz is headquartered in Dublin, Ireland with research and development laboratories, manufacturing facilities and employees in multiple countries committed to serving patients worldwide. Please visit for more information. The Senior Principal will be responsible for leading projects related to data engineering requirements and initiatives across Jazz Research and Development. The Senior Principal will lead data projects from across the business including Clinical, Pre-Clinical, Non-Clinical, Chemistry, RWD and Omics. Essential Functions Lead the design, development and maintenance of data pipelines for processing Research and Development data from diverse sources (Clinical Trials, Medical Devices, Pre-Clinical, Omics, Real World Data) utilizing the AWS technology platform. Create and optimize ETL/ELT processes for structured and unstructured data using Python, R, SQL, AWS services and other tools. Build and maintain data repositories using AWS S3 and FSx technologies. Establish data warehousing solutions using Amazon Redshift. Build and maintain standard data models. Own data quality frameworks, validation processes and KPIs to ensure accuracy and consistency of data pipelines. Implement data versioning and lineage tracking to support data traceability, regulatory compliance and audit requirements. Create and maintain documentation for data processes, architectures, and workflows. Implement modern software development best practices (e.g. Code Versioning, DevOps, CD/CI). Support collaboration with RnD Researchers, Data scientists and Stakeholders to understand data requirements and deliver appropriate solutions in a global working model. Maintain compliance with data privacy regulations such as HIPAA, GDPR May be required to develop, deliver or support data literacy training across R&D. Required Knowledge, Skills and Abilities Expert knowledge of data engineering tools such as Python, R and SQL for data processing. Expert proficiency with AWS services particularly S3, Redshift, FSx, Glue, Lambda. Expert proficiency with relational databases. Strong background in data modeling and database design. Strong knowledge with unstructured database technologies (e.g. NoSQL) and other database types (e.g. Graph). Experience with Containerization such as Docker and EKS/Kubernetes. Experience with one or more RnD research process and associated regulatory requirements. Exposure to healthcare data standards (CDISC, HL7, FHIR, SNOMED CT, OMOP, DICOM). Experience to big data technologies and handling. Knowledge of machine learning operations (MLOps) and model deployment. Strong problem-solving and analytical abilities. Excellent communication skills for collaborating with stakeholders. Experience working in an Agile development environment. Required/Preferred Education Bachelor's Degree in Computer Science, Statistics, Mathematics, Life Sciences, or other relevant scientific fields; Master's Degree preferred 5-7 years of experience in data engineering, with at least 2 years focusing on healthcare, research or clinical related data Description of Physical Demands Occasional mobility within office environment Routinely sitting for extended periods of time Constantly operating a computer, printer, telephone and other similar office machinery Jazz Pharmaceuticals is an equal opportunity/affirmative action employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, or any characteristic protected by law. The successful candidate will also be eligible to participate in various benefits offerings, including, but not limited to, medical, dental and vision insurance, retirement savings plan, and flexible paid vacation. For more information on our Benefits offerings please click here: .
Oct 04, 2025
Full time
If you are a current Jazz employee please apply via the Internal Career site. Jazz Pharmaceuticals is a global biopharma company whose purpose is to innovate to transform the lives of patients and their families. We are dedicated to developing life-changing medicines for people with serious diseases - often with limited or no therapeutic options. We have a diverse portfolio of marketed medicines, including leading therapies for sleep disorders and epilepsy, and a growing portfolio of cancer treatments. Our patient-focused and science-driven approach powers pioneering research and development advancements across our robust pipeline of innovative therapeutics in oncology and neuroscience. Jazz is headquartered in Dublin, Ireland with research and development laboratories, manufacturing facilities and employees in multiple countries committed to serving patients worldwide. Please visit for more information. The Senior Principal will be responsible for leading projects related to data engineering requirements and initiatives across Jazz Research and Development. The Senior Principal will lead data projects from across the business including Clinical, Pre-Clinical, Non-Clinical, Chemistry, RWD and Omics. Essential Functions Lead the design, development and maintenance of data pipelines for processing Research and Development data from diverse sources (Clinical Trials, Medical Devices, Pre-Clinical, Omics, Real World Data) utilizing the AWS technology platform. Create and optimize ETL/ELT processes for structured and unstructured data using Python, R, SQL, AWS services and other tools. Build and maintain data repositories using AWS S3 and FSx technologies. Establish data warehousing solutions using Amazon Redshift. Build and maintain standard data models. Own data quality frameworks, validation processes and KPIs to ensure accuracy and consistency of data pipelines. Implement data versioning and lineage tracking to support data traceability, regulatory compliance and audit requirements. Create and maintain documentation for data processes, architectures, and workflows. Implement modern software development best practices (e.g. Code Versioning, DevOps, CD/CI). Support collaboration with RnD Researchers, Data scientists and Stakeholders to understand data requirements and deliver appropriate solutions in a global working model. Maintain compliance with data privacy regulations such as HIPAA, GDPR May be required to develop, deliver or support data literacy training across R&D. Required Knowledge, Skills and Abilities Expert knowledge of data engineering tools such as Python, R and SQL for data processing. Expert proficiency with AWS services particularly S3, Redshift, FSx, Glue, Lambda. Expert proficiency with relational databases. Strong background in data modeling and database design. Strong knowledge with unstructured database technologies (e.g. NoSQL) and other database types (e.g. Graph). Experience with Containerization such as Docker and EKS/Kubernetes. Experience with one or more RnD research process and associated regulatory requirements. Exposure to healthcare data standards (CDISC, HL7, FHIR, SNOMED CT, OMOP, DICOM). Experience to big data technologies and handling. Knowledge of machine learning operations (MLOps) and model deployment. Strong problem-solving and analytical abilities. Excellent communication skills for collaborating with stakeholders. Experience working in an Agile development environment. Required/Preferred Education Bachelor's Degree in Computer Science, Statistics, Mathematics, Life Sciences, or other relevant scientific fields; Master's Degree preferred 5-7 years of experience in data engineering, with at least 2 years focusing on healthcare, research or clinical related data Description of Physical Demands Occasional mobility within office environment Routinely sitting for extended periods of time Constantly operating a computer, printer, telephone and other similar office machinery Jazz Pharmaceuticals is an equal opportunity/affirmative action employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, or any characteristic protected by law. The successful candidate will also be eligible to participate in various benefits offerings, including, but not limited to, medical, dental and vision insurance, retirement savings plan, and flexible paid vacation. For more information on our Benefits offerings please click here: .
If you are a current Jazz employee please apply via the Internal Career site. Jazz Pharmaceuticals is a global biopharma company whose purpose is to innovate to transform the lives of patients and their families. We are dedicated to developing life-changing medicines for people with serious diseases - often with limited or no therapeutic options. We have a diverse portfolio of marketed medicines, including leading therapies for sleep disorders and epilepsy, and a growing portfolio of cancer treatments. Our patient-focused and science-driven approach powers pioneering research and development advancements across our robust pipeline of innovative therapeutics in oncology and neuroscience. Jazz is headquartered in Dublin, Ireland with research and development laboratories, manufacturing facilities and employees in multiple countries committed to serving patients worldwide. Please visit for more information. Job Role: We are looking for dynamic, creative, and talented computational chemist to join our expanding Discovery & Medicinal Chemistry Department. Reporting to the Director of Medicinal Chemistry, you will apply your expertise, leadership and guidance to discover and develop novel small-molecule therapeutic agents. You will be working within a patient-focused, science-driven, and multi-disciplinary biopharmaceutical environment, covering all stages of the drug discovery process. You will collaborate with scientists from other disciplines within Jazz Pharmaceuticals and with external collaborators to build an innovative portfolio of therapeutics across our exciting and growing oncology and neuroscience pipelines. Working at the forefront of drug discovery you will advance projects from target selection to preclinical drug candidates and FiH trials, and contribute to the growth of the medicinal chemistry team. Key Responsibilities: Utilize modern molecular modelling methods to support different stages of R&D programs. Collaborate effectively with other departments and functions to advance research discovery projects expeditiously from hit identification to high quality preclinical candidates. Design, lead and drive computational studies on projects throughout the several discovery phases and ensure execution on agreed deliverables. Opportunities to lead or co-lead projects in addition to drive discipline-specific endeavours. Set the vision and strategy for computational chemistry. Foster innovative thinking in all areas of departmental activities, with a particular focus on computational and medicinal chemistry. Manage CRO compchem activities, providing expertise and guidance. Present plans and results internally, including at board level, and externally at conferences. Contribute to the writing of patent applications, scientific publications, and internal reports. Develop and mentor less experienced staff. Keep up to date with the latest scientific advances and trends in drug discovery to deliver the next-generation therapies. Undertake ongoing professional development by attending relevant training and conferences. Requirements & Qualifications: MSc/PhD in a relevant scientific discipline (Pharmaceutical Sciences, Chemistry, Computational Chemistry) with a solid foundation in molecular modelling built in a pharma/biotech/CRO setting. Expert knowledge in CADD software packages and modern molecular modelling techniques. Sound knowledge in cutting-edge cheminformatic tools, AI/ML-enabled technologies, and in silico drug design, including both structure- and ligand-based methodologies. Passion for drug discovery with a deep entrepreneurial and problem-solving attitude. Mastery of all the theoretical and practical principles of medicinal chemistry and drug design. Broad knowledge of biophysical, biochemical, and cell-based assays used in the early stages of the drug discovery process. In depth understanding of multi-parameter optimization and ability to integrate disease biology, ADME/DMPK and toxicology data to solve complex drug discovery problems. Excellent leadership, management, organizational and team-working skills, and a talent to deliver project milestones within the expected time frame. Demonstrated track record of scientific publications. Exceptional oral, written, and interpersonal communication skills, and ability to develop and grow strong cross-functional collaborations. Jazz Pharmaceuticals is an equal opportunity/affirmative action employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, or any characteristic protected by law. The successful candidate will also be eligible to participate in various benefits offerings, including, but not limited to, medical, dental and vision insurance, retirement savings plan, and flexible paid vacation. For more information on our Benefits offerings please click here: .
Oct 04, 2025
Full time
If you are a current Jazz employee please apply via the Internal Career site. Jazz Pharmaceuticals is a global biopharma company whose purpose is to innovate to transform the lives of patients and their families. We are dedicated to developing life-changing medicines for people with serious diseases - often with limited or no therapeutic options. We have a diverse portfolio of marketed medicines, including leading therapies for sleep disorders and epilepsy, and a growing portfolio of cancer treatments. Our patient-focused and science-driven approach powers pioneering research and development advancements across our robust pipeline of innovative therapeutics in oncology and neuroscience. Jazz is headquartered in Dublin, Ireland with research and development laboratories, manufacturing facilities and employees in multiple countries committed to serving patients worldwide. Please visit for more information. Job Role: We are looking for dynamic, creative, and talented computational chemist to join our expanding Discovery & Medicinal Chemistry Department. Reporting to the Director of Medicinal Chemistry, you will apply your expertise, leadership and guidance to discover and develop novel small-molecule therapeutic agents. You will be working within a patient-focused, science-driven, and multi-disciplinary biopharmaceutical environment, covering all stages of the drug discovery process. You will collaborate with scientists from other disciplines within Jazz Pharmaceuticals and with external collaborators to build an innovative portfolio of therapeutics across our exciting and growing oncology and neuroscience pipelines. Working at the forefront of drug discovery you will advance projects from target selection to preclinical drug candidates and FiH trials, and contribute to the growth of the medicinal chemistry team. Key Responsibilities: Utilize modern molecular modelling methods to support different stages of R&D programs. Collaborate effectively with other departments and functions to advance research discovery projects expeditiously from hit identification to high quality preclinical candidates. Design, lead and drive computational studies on projects throughout the several discovery phases and ensure execution on agreed deliverables. Opportunities to lead or co-lead projects in addition to drive discipline-specific endeavours. Set the vision and strategy for computational chemistry. Foster innovative thinking in all areas of departmental activities, with a particular focus on computational and medicinal chemistry. Manage CRO compchem activities, providing expertise and guidance. Present plans and results internally, including at board level, and externally at conferences. Contribute to the writing of patent applications, scientific publications, and internal reports. Develop and mentor less experienced staff. Keep up to date with the latest scientific advances and trends in drug discovery to deliver the next-generation therapies. Undertake ongoing professional development by attending relevant training and conferences. Requirements & Qualifications: MSc/PhD in a relevant scientific discipline (Pharmaceutical Sciences, Chemistry, Computational Chemistry) with a solid foundation in molecular modelling built in a pharma/biotech/CRO setting. Expert knowledge in CADD software packages and modern molecular modelling techniques. Sound knowledge in cutting-edge cheminformatic tools, AI/ML-enabled technologies, and in silico drug design, including both structure- and ligand-based methodologies. Passion for drug discovery with a deep entrepreneurial and problem-solving attitude. Mastery of all the theoretical and practical principles of medicinal chemistry and drug design. Broad knowledge of biophysical, biochemical, and cell-based assays used in the early stages of the drug discovery process. In depth understanding of multi-parameter optimization and ability to integrate disease biology, ADME/DMPK and toxicology data to solve complex drug discovery problems. Excellent leadership, management, organizational and team-working skills, and a talent to deliver project milestones within the expected time frame. Demonstrated track record of scientific publications. Exceptional oral, written, and interpersonal communication skills, and ability to develop and grow strong cross-functional collaborations. Jazz Pharmaceuticals is an equal opportunity/affirmative action employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, or any characteristic protected by law. The successful candidate will also be eligible to participate in various benefits offerings, including, but not limited to, medical, dental and vision insurance, retirement savings plan, and flexible paid vacation. For more information on our Benefits offerings please click here: .
